Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2266079..2266295 Replicon chromosome
Accession NZ_CP033982
Organism Staphylococcus aureus strain P2D8C1

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EFD77_RS11465 Protein ID WP_001802298.1
Coordinates 2266191..2266295 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2266079..2266134 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFD77_RS11445 2262285..2262950 - 666 WP_001024095.1 SDR family oxidoreductase -
EFD77_RS11450 2263102..2263422 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EFD77_RS11455 2263424..2264401 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
EFD77_RS11460 2264667..2265758 + 1092 WP_156668041.1 transcriptional regulator -
- 2266079..2266134 + 56 - - Antitoxin
EFD77_RS11465 2266191..2266295 - 105 WP_001802298.1 hypothetical protein Toxin
EFD77_RS11470 2266975..2267133 + 159 WP_001792784.1 hypothetical protein -
EFD77_RS11475 2267791..2268648 - 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
EFD77_RS11480 2268716..2269498 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T114790 WP_001802298.1 NZ_CP033982:c2266295-2266191 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T114790 NZ_CP033982:c2266295-2266191 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT114790 NZ_CP033982:2266079-2266134 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References