Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1276204..1276717 Replicon chromosome
Accession NZ_CP033898
Organism Corynebacterium pseudopelargi strain 812CH

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CPPEL_RS05980 Protein ID WP_123961253.1
Coordinates 1276460..1276717 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CPPEL_RS05975 Protein ID WP_123960271.1
Coordinates 1276204..1276458 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPPEL_RS05955 1271414..1271593 - 180 WP_123960267.1 hypothetical protein -
CPPEL_RS05960 1272372..1272914 - 543 WP_123960268.1 hypothetical protein -
CPPEL_RS05965 1273539..1274033 - 495 WP_123960269.1 hypothetical protein -
CPPEL_RS05970 1275367..1275936 - 570 WP_123960270.1 hypothetical protein -
CPPEL_RS05975 1276204..1276458 + 255 WP_123960271.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CPPEL_RS05980 1276460..1276717 + 258 WP_123961253.1 Txe/YoeB family addiction module toxin Toxin
CPPEL_RS05985 1276788..1277084 - 297 WP_123960272.1 GNAT family N-acetyltransferase -
CPPEL_RS11210 1277181..1277654 + 474 WP_206608917.1 DUF4118 domain-containing protein -
CPPEL_RS11215 1277842..1278580 + 739 Protein_1171 response regulator transcription factor -
CPPEL_RS05995 1278655..1279902 - 1248 WP_164470385.1 esterase family protein -
CPPEL_RS06000 1280092..1280889 + 798 WP_123960274.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1267442..1276717 9275


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10387.71 Da        Isoelectric Point: 8.0410

>T114630 WP_123961253.1 NZ_CP033898:1276460-1276717 [Corynebacterium pseudopelargi]
MLLVWDENAWEDYLWWQTQDRRTLKRINQLIKDIDRNGNEGIGKPEPLKHSLAGYWSRRITDEHRLVYRTIDNEIRIASC
RYHYG

Download         Length: 258 bp

>T114630 NZ_CP033898:1276460-1276717 [Corynebacterium pseudopelargi]
ATGCTCTTGGTCTGGGATGAGAACGCTTGGGAAGACTACCTCTGGTGGCAAACCCAAGACCGCAGAACGTTGAAACGCAT
CAACCAACTCATCAAGGACATCGACCGCAATGGCAACGAGGGCATCGGGAAACCGGAGCCGCTCAAGCATAGTCTGGCTG
GCTACTGGTCACGGCGCATCACTGATGAACATCGCCTGGTGTACAGGACAATAGACAACGAGATTCGTATTGCATCCTGC
CGCTACCACTACGGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9646.70 Da        Isoelectric Point: 4.5578

>AT114630 WP_123960271.1 NZ_CP033898:1276204-1276458 [Corynebacterium pseudopelargi]
MKTMNYTESRANYAKVLDDVVNDREETIITRAGHESVVIVSLEEYESLKETAYLLRSPANARRLFESIDRLEANRGSEHS
LIDD

Download         Length: 255 bp

>AT114630 NZ_CP033898:1276204-1276458 [Corynebacterium pseudopelargi]
ATGAAAACAATGAACTACACCGAGTCGCGGGCGAACTACGCCAAAGTCCTCGACGACGTGGTGAATGACCGCGAGGAAAC
AATCATCACCCGCGCGGGTCACGAATCAGTCGTTATCGTATCCCTGGAAGAATACGAATCCCTCAAAGAGACCGCCTACC
TGCTCCGATCACCAGCCAATGCCCGTCGACTTTTCGAGTCGATAGACAGACTCGAGGCAAACCGAGGCAGCGAGCACTCT
CTCATCGATGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References