114545

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2041456..2041640 Replicon chromosome
Accession NZ_CP033865
Organism Staphylococcus aureus strain FDAARGOS_504

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag EG363_RS10880 Protein ID WP_000482647.1
Coordinates 2041533..2041640 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2041456..2041516 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EG363_RS10855 2036966..2037133 - 168 Protein_2026 hypothetical protein -
EG363_RS10865 2037364..2039097 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
EG363_RS10870 2039122..2040885 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2041456..2041516 + 61 - - Antitoxin
EG363_RS10880 2041533..2041640 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
EG363_RS10885 2041774..2042160 - 387 WP_000779351.1 flippase GtxA -
EG363_RS10890 2042428..2043570 + 1143 WP_001176857.1 glycerate kinase -
EG363_RS10895 2043630..2044289 + 660 WP_000831298.1 membrane protein -
EG363_RS10900 2044471..2045682 + 1212 WP_001191920.1 multidrug effflux MFS transporter -
EG363_RS10905 2045805..2046278 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T114545 WP_000482647.1 NZ_CP033865:c2041640-2041533 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T114545 NZ_CP033865:c2041640-2041533 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT114545 NZ_CP033865:2041456-2041516 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References