Detailed information of TA system TA114543

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG3-sprA1AS/-
• Location: 1756446..1756643
• Replicon: chromosome
• Accession: NZ_CP033865
• Organism: Staphylococcus aureus strain FDAARGOS_504

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: EG363_RS09330
• Protein ID: WP_073392962.1
• Coordinates: 1756539..1756643 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1756446..1756484 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EG363_RS09310	1752621..1753286	-	666	WP_001024099.1	SDR family oxidoreductase	-
EG363_RS09315	1753438..1753758	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
EG363_RS09320	1753760..1754740	+	981	WP_000019741.1	CDF family zinc efflux transporter CzrB	-
EG363_RS09325	1755006..1756097	+	1092	WP_000495684.1	hypothetical protein	-
-	1756446..1756484	+	39	-	-	Antitoxin
EG363_RS09330	1756539..1756643	-	105	WP_073392962.1	hypothetical protein	Toxin
EG363_RS09340	1757323..1757481	+	159	WP_001792784.1	hypothetical protein	-
EG363_RS09350	1758140..1758997	-	858	WP_000370937.1	Cof-type HAD-IIB family hydrolase	-
EG363_RS09355	1759065..1759847	-	783	WP_124095538.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T114543 WP_073392962.1 NZ_CP033865:c1756643-1756539 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T114543 NZ_CP033865:c1756643-1756539 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 39 bp

>AT114543 NZ_CP033865:1756446-1756484 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin