Detailed information of TA system TA114180

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 2395559..2395707
• Replicon: chromosome
• Accession: NZ_CP033735
• Organism: Staphylococcus cohnii strain FDAARGOS_538

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: EGX68_RS12125
• Protein ID: WP_011276848.1
• Coordinates: 2395559..2395654 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2395672..2395707 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EGX68_RS12090	2390915..2391373	+	459	Protein_2301	replication protein	-
EGX68_RS12095	2391318..2391623	+	306	Protein_2302	protein rep	-
EGX68_RS12105	2392334..2392834	+	501	WP_103211460.1	MepB family protein	-
EGX68_RS12110	2393018..2393413	+	396	WP_107556030.1	HTH domain-containing protein	-
EGX68_RS12115	2394130..2394543	+	414	WP_070657352.1	hypothetical protein	-
EGX68_RS12120	2394565..2395434	+	870	WP_103211458.1	NERD domain-containing protein	-
EGX68_RS12125	2395559..2395654	+	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2395672..2395707	+	36	-	-	Antitoxin
EGX68_RS12130	2395836..2396654	-	819	WP_046467874.1	aquaporin family protein	-
EGX68_RS12135	2396943..2398562	-	1620	WP_046467873.1	BCCT family transporter	-
EGX68_RS12140	2399156..2399833	+	678	WP_053025666.1	transglycosylase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2390190..2390864	674

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-137)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T114180 WP_011276848.1 NZ_CP033735:2395559-2395654 [Staphylococcus cohnii]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T114180 NZ_CP033735:2395559-2395654 [Staphylococcus cohnii]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT114180 NZ_CP033735:2395672-2395707 [Staphylococcus cohnii]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin