Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 2395559..2395707 Replicon chromosome
Accession NZ_CP033735
Organism Staphylococcus cohnii strain FDAARGOS_538

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag EGX68_RS12125 Protein ID WP_011276848.1
Coordinates 2395559..2395654 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2395672..2395707 (+)

Genomic Context


EGX68_RS12090EGX68_RS12095EGX68_RS12105EGX68_RS12110EGX68_RS12115EGX68_RS12120EGX68_RS12125--EGX68_RS12140EGX68_RS12130EGX68_RS12135
Location: 2390915..2391373 (459 bp)
Type: Others
Protein ID: Protein_2301
Location: 2391318..2391623 (306 bp)
Type: Others
Protein ID: Protein_2302
Location: 2392334..2392834 (501 bp)
Type: Others
Protein ID: WP_103211460.1
Location: 2393018..2393413 (396 bp)
Type: Others
Protein ID: WP_107556030.1
Location: 2394130..2394543 (414 bp)
Type: Others
Protein ID: WP_070657352.1
Location: 2394565..2395434 (870 bp)
Type: Others
Protein ID: WP_103211458.1
Location: 2395559..2395654 (96 bp)
Type: Toxin
Protein ID: WP_011276848.1
Location: 2395672..2395707 (36 bp)
Type: Antitoxin
Protein ID: -
Location: 2399156..2399833 (678 bp)
Type: Others
Protein ID: WP_053025666.1
Location: 2395836..2396654 (819 bp)
Type: Others
Protein ID: WP_046467874.1
Location: 2396943..2398562 (1620 bp)
Type: Others
Protein ID: WP_046467873.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EGX68_RS120902390915..2391373+459Protein_2301replication protein-
EGX68_RS120952391318..2391623+306Protein_2302protein rep-
EGX68_RS121052392334..2392834+501WP_103211460.1MepB family protein-
EGX68_RS121102393018..2393413+396WP_107556030.1HTH domain-containing protein-
EGX68_RS121152394130..2394543+414WP_070657352.1hypothetical protein-
EGX68_RS121202394565..2395434+870WP_103211458.1NERD domain-containing protein-
EGX68_RS121252395559..2395654+96WP_011276848.1type I toxin-antitoxin system Fst family toxinToxin
-2395672..2395707+36--Antitoxin
EGX68_RS121302395836..2396654-819WP_046467874.1aquaporin family protein-
EGX68_RS121352396943..2398562-1620WP_046467873.1BCCT family transporter-
EGX68_RS121402399156..2399833+678WP_053025666.1transglycosylase family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--2390190..2390864674


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-137)


Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3623.38 Da        Isoelectric Point: 9.5124

>T114180 WP_011276848.1 NZ_CP033735:2395559-2395654 [Staphylococcus cohnii]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Download         Length: 96 bp

>T114180 NZ_CP033735:2395559-2395654 [Staphylococcus cohnii]
ATGTTGGAAATCCTTGTTCACATCACGACCACAGTCATCAGTGGTTGTATTATTGCGTTATTTACGCATTGGCTGCGTAA
TCGCAAAGACAAATAG

Antitoxin


Download         Length: 36 bp

>AT114180 NZ_CP033735:2395672-2395707 [Staphylococcus cohnii]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

Download structure file

References