Detailed information of TA system TA113397

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2063099..2063414
• Replicon: chromosome
• Accession: NZ_CP033205
• Organism: Bacillus subtilis strain MBI 600

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: DA787_RS10375
• Protein ID: WP_120322743.1
• Coordinates: 2063099..2063260 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2063241..2063414 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DA787_RS10360	2058327..2058662	+	336	WP_009967409.1	hypothetical protein	-
DA787_RS10365	2058709..2062314	-	3606	WP_137041639.1	hypothetical protein	-
DA787_RS10370	2062547..2062879	-	333	WP_026009814.1	hypothetical protein	-
DA787_RS10375	2063099..2063260	+	162	WP_120322743.1	putative holin-like toxin	Toxin
-	2063241..2063414	-	174	-	-	Antitoxin
DA787_RS10380	2063529..2064371	-	843	WP_003231327.1	hypothetical protein	-
DA787_RS10385	2064571..2065029	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
DA787_RS10390	2065039..2066841	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
DA787_RS10395	2066943..2067500	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2049153..2072831	23678

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (24-47)

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 5780.74 Da
• Isoelectric Point: 4.6641

>T113397 WP_120322743.1 NZ_CP033205:2063099-2063260 [Bacillus subtilis]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 162 bp

>T113397 NZ_CP033205:2063099-2063260 [Bacillus subtilis]
ATTTCCTGTACAGTAAGTTTTGCTCACTCGAGGGAGTCTTGCTCATCCCCTAATGAAAGGGGTGATGCTATGTCAACATT
CCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAATAGACCTCCCTT
GA

Antitoxin

Nucleotide

• Length: 174 bp

>AT113397 NZ_CP033205:c2063414-2063241 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin