Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 743818..744332 Replicon chromosome
Accession NZ_CP033107
Organism Plantibacter sp. PA-3-X8

Toxin (Protein)


Gene name yoeB Uniprot ID A0A1S7BDW8
Locus tag EAO79_RS03595 Protein ID WP_064294057.1
Coordinates 744075..744332 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1S7BDX5
Locus tag EAO79_RS03590 Protein ID WP_064294058.1
Coordinates 743818..744069 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EAO79_RS03560 738919..740001 - 1083 WP_161578587.1 alpha/beta hydrolase -
EAO79_RS03565 740196..740369 + 174 WP_064294062.1 CsbD family protein -
EAO79_RS03570 740466..740729 + 264 WP_064294061.1 GlsB/YeaQ/YmgE family stress response membrane protein -
EAO79_RS03575 741026..741577 - 552 WP_124767818.1 type 1 glutamine amidotransferase -
EAO79_RS03580 741687..742634 - 948 WP_124767819.1 G5 domain-containing protein -
EAO79_RS03585 742723..743667 - 945 WP_124767820.1 DnaJ domain-containing protein -
EAO79_RS03590 743818..744069 + 252 WP_064294058.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EAO79_RS03595 744075..744332 + 258 WP_064294057.1 Txe/YoeB family addiction module toxin Toxin
EAO79_RS03600 744353..745978 - 1626 WP_124767821.1 methyltransferase -
EAO79_RS03605 745941..747317 - 1377 WP_124770053.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10232.63 Da        Isoelectric Point: 8.9976

>T113181 WP_064294057.1 NZ_CP033107:744075-744332 [Plantibacter sp. PA-3-X8]
VRLIWSDAAWEDYCHWQQQDRRIVKRINLLLKDIIRNGNEGIGKPEALKHGFQGFWSRRITDEHRLVYRLTDDGVLIAQA
RFHYE

Download         Length: 258 bp

>T113181 NZ_CP033107:744075-744332 [Plantibacter sp. PA-3-X8]
GTGCGGCTCATCTGGTCCGACGCCGCCTGGGAGGACTACTGCCACTGGCAGCAACAGGATCGGCGCATCGTCAAACGGAT
CAATCTCCTCCTGAAGGACATCATCCGGAACGGCAACGAGGGCATCGGCAAACCTGAGGCGCTCAAGCACGGCTTCCAGG
GATTCTGGTCACGACGGATCACCGACGAACATCGACTGGTCTACCGCCTCACGGACGACGGCGTCCTCATCGCCCAGGCA
CGCTTCCACTACGAGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9225.22 Da        Isoelectric Point: 4.1730

>AT113181 WP_064294058.1 NZ_CP033107:743818-744069 [Plantibacter sp. PA-3-X8]
MRTLSYSESRANYAATLDSVLDDREEVIITRAGRDPVVIVALDDYESLKESAYLLRTPSNARRLLQAIDDLEAGAGTEHD
LVE

Download         Length: 252 bp

>AT113181 NZ_CP033107:743818-744069 [Plantibacter sp. PA-3-X8]
ATGCGTACCCTCAGTTATTCGGAATCCCGCGCGAACTACGCGGCCACCCTCGATTCGGTCCTCGACGACCGCGAGGAGGT
GATCATCACCAGAGCGGGGCGCGACCCGGTCGTGATCGTCGCGCTCGACGACTACGAGTCCTTGAAGGAATCGGCGTATC
TGCTCCGCACGCCGTCGAACGCACGTCGGCTCCTCCAGGCCATCGACGACCTCGAGGCCGGCGCGGGCACCGAGCACGAC
CTGGTCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1S7BDW8

Antitoxin

Source ID Structure
AlphaFold DB A0A1S7BDX5

References