Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | prlF-yhaV (relBE)/YhaV-PrlF |
Location | 1149282..1150072 | Replicon | chromosome |
Accession | NZ_CP033104 | ||
Organism | Pseudomonas sp. LTGT-11-2Z |
Toxin (Protein)
Gene name | yhaV | Uniprot ID | A0A3G2HLC0 |
Locus tag | D8767_RS05215 | Protein ID | WP_016713503.1 |
Coordinates | 1149282..1149749 (-) | Length | 156 a.a. |
Antitoxin (Protein)
Gene name | prlF | Uniprot ID | A0A0P7D0H8 |
Locus tag | D8767_RS05220 | Protein ID | WP_016713504.1 |
Coordinates | 1149746..1150072 (-) | Length | 109 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D8767_RS05195 | 1144472..1146001 | + | 1530 | WP_016713500.1 | efflux transporter outer membrane subunit | - |
D8767_RS05200 | 1145998..1148175 | + | 2178 | WP_016713501.1 | FUSC family protein | - |
D8767_RS05205 | 1148165..1148365 | + | 201 | WP_009685040.1 | DUF1656 domain-containing protein | - |
D8767_RS05210 | 1148376..1149236 | + | 861 | WP_121757793.1 | HlyD family secretion protein | - |
D8767_RS05215 | 1149282..1149749 | - | 468 | WP_016713503.1 | type II toxin-antitoxin system YhaV family toxin | Toxin |
D8767_RS05220 | 1149746..1150072 | - | 327 | WP_016713504.1 | type II toxin-antitoxin system PrlF family antitoxin | Antitoxin |
D8767_RS05225 | 1150166..1150612 | - | 447 | WP_016713505.1 | universal stress protein | - |
D8767_RS05230 | 1150883..1151788 | + | 906 | WP_016713506.1 | LysR family transcriptional regulator | - |
D8767_RS05235 | 1151905..1153446 | + | 1542 | WP_016713507.1 | MFS transporter | - |
D8767_RS05240 | 1153475..1154536 | + | 1062 | WP_016713508.1 | HlyD family secretion protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 156 a.a. Molecular weight: 18037.56 Da Isoelectric Point: 10.0504
>T113160 WP_016713503.1 NZ_CP033104:c1149749-1149282 [Pseudomonas sp. LTGT-11-2Z]
MSDASRKPLVIHGWTVIAHPLFLAKLEALSAQVQAQMHKDPTGYTRRNAYKRLAAIKRLAFDVIPQDPTKPEYRQGATLG
GDHKHWFRAKFFQQYRLFFRYHTPSRIIVLAWVNDESSKRAYESSDDAYKVFQKMLHTGHPPDDWEQLLREAAAE
MSDASRKPLVIHGWTVIAHPLFLAKLEALSAQVQAQMHKDPTGYTRRNAYKRLAAIKRLAFDVIPQDPTKPEYRQGATLG
GDHKHWFRAKFFQQYRLFFRYHTPSRIIVLAWVNDESSKRAYESSDDAYKVFQKMLHTGHPPDDWEQLLREAAAE
Download Length: 468 bp
>T113160 NZ_CP033104:c1149749-1149282 [Pseudomonas sp. LTGT-11-2Z]
ATGAGTGATGCGAGCAGGAAGCCTCTGGTTATTCATGGATGGACTGTAATTGCCCACCCGCTGTTCCTGGCCAAACTGGA
GGCACTCAGCGCTCAAGTGCAGGCTCAGATGCACAAGGACCCAACGGGTTACACGCGCAGAAATGCCTATAAAAGGCTGG
CGGCCATCAAGCGACTGGCCTTCGATGTAATCCCTCAAGACCCGACCAAACCTGAGTACCGGCAGGGGGCCACACTGGGT
GGTGACCACAAGCACTGGTTCAGGGCAAAGTTCTTCCAGCAGTACCGGTTGTTCTTCCGCTATCACACCCCCAGCAGGAT
CATTGTGCTGGCCTGGGTCAATGACGAGTCGAGCAAGCGGGCCTACGAAAGTAGCGACGATGCTTACAAGGTCTTTCAGA
AGATGCTGCATACCGGCCACCCGCCGGACGATTGGGAGCAGCTACTGCGAGAAGCTGCAGCCGAATGA
ATGAGTGATGCGAGCAGGAAGCCTCTGGTTATTCATGGATGGACTGTAATTGCCCACCCGCTGTTCCTGGCCAAACTGGA
GGCACTCAGCGCTCAAGTGCAGGCTCAGATGCACAAGGACCCAACGGGTTACACGCGCAGAAATGCCTATAAAAGGCTGG
CGGCCATCAAGCGACTGGCCTTCGATGTAATCCCTCAAGACCCGACCAAACCTGAGTACCGGCAGGGGGCCACACTGGGT
GGTGACCACAAGCACTGGTTCAGGGCAAAGTTCTTCCAGCAGTACCGGTTGTTCTTCCGCTATCACACCCCCAGCAGGAT
CATTGTGCTGGCCTGGGTCAATGACGAGTCGAGCAAGCGGGCCTACGAAAGTAGCGACGATGCTTACAAGGTCTTTCAGA
AGATGCTGCATACCGGCCACCCGCCGGACGATTGGGAGCAGCTACTGCGAGAAGCTGCAGCCGAATGA
Antitoxin
Download Length: 109 a.a. Molecular weight: 12007.46 Da Isoelectric Point: 4.3118
>AT113160 WP_016713504.1 NZ_CP033104:c1150072-1149746 [Pseudomonas sp. LTGT-11-2Z]
MATTLDVESTLTDRYQTTVPETVRRALGLKKRDKIHYSIRPDGEVILTRAEATESDPVLGKFLDFLAHDIATNPQRLQVV
DADLIARLDKLVGDAEVDLDQSLSADDE
MATTLDVESTLTDRYQTTVPETVRRALGLKKRDKIHYSIRPDGEVILTRAEATESDPVLGKFLDFLAHDIATNPQRLQVV
DADLIARLDKLVGDAEVDLDQSLSADDE
Download Length: 327 bp
>AT113160 NZ_CP033104:c1150072-1149746 [Pseudomonas sp. LTGT-11-2Z]
ATGGCAACCACTCTCGACGTCGAGTCCACACTGACCGATCGCTATCAGACCACTGTTCCCGAAACAGTACGGCGCGCCTT
GGGCTTGAAAAAACGTGACAAGATCCATTACTCGATTCGCCCTGACGGTGAGGTGATACTCACCCGTGCAGAAGCAACCG
AGAGCGATCCAGTACTGGGCAAATTTCTGGATTTCCTGGCACACGATATCGCCACCAACCCTCAACGGCTGCAGGTTGTC
GATGCTGACCTCATCGCGCGTCTCGACAAGCTTGTCGGCGACGCAGAGGTCGACCTGGATCAATCTCTGTCGGCGGATGA
TGAATGA
ATGGCAACCACTCTCGACGTCGAGTCCACACTGACCGATCGCTATCAGACCACTGTTCCCGAAACAGTACGGCGCGCCTT
GGGCTTGAAAAAACGTGACAAGATCCATTACTCGATTCGCCCTGACGGTGAGGTGATACTCACCCGTGCAGAAGCAACCG
AGAGCGATCCAGTACTGGGCAAATTTCTGGATTTCCTGGCACACGATATCGCCACCAACCCTCAACGGCTGCAGGTTGTC
GATGCTGACCTCATCGCGCGTCTCGACAAGCTTGTCGGCGACGCAGAGGTCGACCTGGATCAATCTCTGTCGGCGGATGA
TGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G2HLC0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0P7D0H8 |