Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 1005811..1005972 Replicon chromosome
Accession NZ_CP033098
Organism Staphylococcus warneri strain SWO

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag EAH52_RS05025 Protein ID WP_015364873.1
Coordinates 1005811..1005906 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1005938..1005972 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EAH52_RS05015 1001782..1004715 + 2934 WP_002466810.1 AAA family ATPase -
EAH52_RS05020 1004715..1005656 + 942 WP_002466800.1 3'-5' exoribonuclease YhaM -
EAH52_RS05025 1005811..1005906 + 96 WP_015364873.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1005938..1005972 - 35 - - Antitoxin
EAH52_RS05030 1006058..1007050 - 993 WP_002466825.1 peptidylprolyl isomerase -
EAH52_RS05035 1007228..1007785 - 558 WP_002466819.1 DUF3267 domain-containing protein -
EAH52_RS05040 1007980..1008351 - 372 WP_031464024.1 YtxH domain-containing protein -
EAH52_RS05045 1008429..1008854 - 426 WP_002466803.1 HIT family protein -
EAH52_RS05050 1008986..1009726 + 741 WP_002466806.1 ABC transporter ATP-binding protein -
EAH52_RS05055 1009719..1010942 + 1224 WP_002466814.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-128)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3610.26 Da        Isoelectric Point: 8.0878

>T113136 WP_015364873.1 NZ_CP033098:1005811-1005906 [Staphylococcus warneri]
MTEIFVHIATTVISGCIVTLFAHWLRHRNDK

Download         Length: 96 bp

>T113136 NZ_CP033098:1005811-1005906 [Staphylococcus warneri]
ATGACTGAAATCTTTGTTCATATCGCAACTACTGTTATTAGTGGTTGTATCGTTACATTATTTGCGCATTGGCTACGCCA
TCGTAACGACAAGTAA

Antitoxin


Download         Length: 35 bp

>AT113136 NZ_CP033098:c1005972-1005938 [Staphylococcus warneri]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References