Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 877121..877726 Replicon chromosome
Accession NZ_CP033076
Organism Buttiauxella sp. 3AFRM03

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag D8682_RS05455 Protein ID WP_121815644.1
Coordinates 877121..877432 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag D8682_RS05460 Protein ID WP_121813733.1
Coordinates 877433..877726 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8682_RS05440 873110..875128 + 2019 WP_121813731.1 heparinase II/III family protein -
D8682_RS05445 875277..876620 + 1344 WP_121813732.1 anaerobic C4-dicarboxylate transporter -
D8682_RS05450 876661..876912 - 252 WP_034496127.1 DUF2766 domain-containing protein -
D8682_RS05455 877121..877432 + 312 WP_121815644.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D8682_RS05460 877433..877726 + 294 WP_121813733.1 helix-turn-helix domain-containing protein Antitoxin
D8682_RS05465 877733..878710 - 978 WP_121813734.1 ABC transporter ATP-binding protein -
D8682_RS05470 878697..879680 - 984 WP_121813735.1 ABC transporter ATP-binding protein -
D8682_RS05475 879673..880518 - 846 WP_121813736.1 ABC transporter permease -
D8682_RS05480 880523..881476 - 954 WP_064545752.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-88)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12154.07 Da        Isoelectric Point: 9.5093

>T113059 WP_121815644.1 NZ_CP033076:877121-877432 [Buttiauxella sp. 3AFRM03]
MLFIETPIFTEDVNALLTDEEYRLFQVFLTFSPESGDVIPHTGGLRKVRWPAKNKGKRSGVRVIYFHKNVDSIIRLLLIY
PKGVKDDLDEAEKRFLRQMNERW

Download         Length: 312 bp

>T113059 NZ_CP033076:877121-877432 [Buttiauxella sp. 3AFRM03]
ATGCTTTTTATCGAAACGCCCATTTTTACAGAGGATGTCAACGCACTGCTCACGGATGAAGAATACCGATTGTTTCAGGT
ATTCCTGACGTTTTCCCCGGAAAGCGGCGATGTGATTCCCCATACTGGTGGCCTGCGTAAAGTGCGGTGGCCTGCAAAAA
ACAAGGGAAAACGCAGTGGCGTTAGAGTCATCTATTTCCATAAAAACGTCGATAGCATCATCAGACTATTGCTGATTTAC
CCGAAAGGGGTCAAAGACGATCTGGATGAAGCGGAAAAACGTTTTTTGCGGCAAATGAACGAGAGGTGGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10785.36 Da        Isoelectric Point: 10.1757

>AT113059 WP_121813733.1 NZ_CP033076:877433-877726 [Buttiauxella sp. 3AFRM03]
MDKQLFARLSESMTQMNEIVEGKREPSRVTEVTATQVKTIRQATGLSQAGFARLISVSVDTLKNWEQGRREPTGPAKALL
RAIENDPEHVILALAPR

Download         Length: 294 bp

>AT113059 NZ_CP033076:877433-877726 [Buttiauxella sp. 3AFRM03]
ATGGATAAACAACTGTTCGCGCGTCTGTCTGAAAGCATGACGCAAATGAATGAGATTGTAGAAGGTAAACGCGAGCCATC
TCGCGTAACGGAAGTCACCGCGACTCAGGTCAAAACCATTCGTCAGGCGACGGGGTTATCGCAGGCCGGTTTTGCCCGGC
TGATCTCCGTGAGCGTCGATACGCTGAAAAACTGGGAGCAAGGCCGCCGTGAACCGACAGGCCCAGCCAAAGCATTACTA
CGTGCGATCGAGAATGACCCTGAACATGTCATTCTCGCTCTGGCACCACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References