Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 16836..17697 Replicon plasmid pBTX_120
Accession NZ_CP033074
Organism Buttiauxella sp. 3AFRM03

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag D8682_RS00155 Protein ID WP_121813096.1
Coordinates 17203..17697 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag D8682_RS00150 Protein ID WP_121813192.1
Coordinates 16836..17180 (+) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8682_RS00110 13282..13728 + 447 WP_121813191.1 DUF1419 domain-containing protein -
D8682_RS00115 13800..14069 + 270 WP_121813089.1 hypothetical protein -
D8682_RS00120 14110..14481 + 372 WP_121813090.1 hypothetical protein -
D8682_RS00125 14474..14992 + 519 WP_121813091.1 hypothetical protein -
D8682_RS00130 15141..15422 + 282 WP_121813092.1 hypothetical protein -
D8682_RS00135 15528..15788 + 261 WP_121813093.1 DUF1380 family protein -
D8682_RS00140 15782..16009 + 228 WP_121813094.1 hypothetical protein -
D8682_RS00145 16264..16485 + 222 WP_121813095.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
D8682_RS00150 16836..17180 + 345 WP_121813192.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
D8682_RS00155 17203..17697 + 495 WP_121813096.1 type II toxin-antitoxin system YhaV family toxin Toxin
D8682_RS00165 18207..18890 + 684 WP_121813098.1 hypothetical protein -
D8682_RS00170 18960..19175 + 216 WP_121813099.1 hypothetical protein -
D8682_RS00175 19293..19967 + 675 WP_121813100.1 DUF4942 domain-containing protein -
D8682_RS00180 20028..20725 + 698 WP_121813101.1 IS1 family transposase -
D8682_RS00185 20816..21064 - 249 WP_121813193.1 hypothetical protein -
D8682_RS00190 21300..21575 + 276 WP_121813102.1 hypothetical protein -
D8682_RS00195 21586..21861 + 276 WP_121813103.1 hypothetical protein -
D8682_RS26560 22015..22290 + 276 WP_162302949.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..120955 120955


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(11-147)

Antitoxin

PrlF antitoxin

(16-114)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 19097.84 Da        Isoelectric Point: 8.4122

>T113045 WP_121813096.1 NZ_CP033074:17203-17697 [Buttiauxella sp. 3AFRM03]
MEYVELNGWKIFFHSCFLKQIAELTEKVVALKASKPNEYKGKKETKLLKAIERVIEERIATDPFNPQYRQGDTLGDEYKH
WFRAKFLSQFRLFYRCSDEYKTIIIGWVNDFDTLRAYGSKTDAYKVFSGMLKAGEPPEDWDTLLTQAKKATSTTSIPGFL
DNQI

Download         Length: 495 bp

>T113045 NZ_CP033074:17203-17697 [Buttiauxella sp. 3AFRM03]
ATGGAATACGTAGAGTTAAACGGGTGGAAAATCTTCTTTCATTCATGCTTTCTGAAGCAGATTGCAGAATTGACTGAGAA
GGTAGTGGCTTTAAAAGCTTCAAAGCCAAATGAATACAAAGGCAAGAAGGAAACCAAGCTCCTGAAGGCGATTGAGCGCG
TGATTGAGGAACGGATAGCAACCGATCCCTTCAATCCGCAATACCGTCAGGGAGATACGTTAGGCGATGAATATAAACAC
TGGTTCCGCGCCAAGTTTCTTTCGCAGTTCCGTTTGTTCTATCGTTGCAGCGATGAGTACAAAACTATCATTATCGGTTG
GGTTAACGATTTCGATACCCTACGCGCTTACGGCTCTAAAACGGACGCCTACAAGGTGTTTTCAGGGATGCTAAAGGCAG
GAGAGCCGCCTGAAGACTGGGATACACTTCTCACTCAGGCAAAGAAAGCCACTTCCACAACCTCTATTCCTGGTTTCCTC
GATAATCAAATCTAG

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12796.53 Da        Isoelectric Point: 4.4227

>AT113045 WP_121813192.1 NZ_CP033074:16836-17180 [Buttiauxella sp. 3AFRM03]
MATQYLNSADVSLRAESRLTERSQTTIPAAIRDALHLKPGEYIKYTLMAGGKVIMSRQEEEQDDPVVSQFLTFLENDMKK
NPQNIHPVPVMFWDSMKALTAGVEVDLDAPLTDD

Download         Length: 345 bp

>AT113045 NZ_CP033074:16836-17180 [Buttiauxella sp. 3AFRM03]
ATGGCTACTCAATATTTAAACAGTGCGGATGTGTCACTGCGTGCTGAGTCTCGACTCACCGAACGCAGCCAGACAACGAT
CCCGGCAGCAATACGCGATGCCTTGCACCTCAAGCCTGGGGAGTACATTAAGTACACCTTGATGGCTGGCGGTAAAGTCA
TCATGTCCCGACAGGAAGAAGAACAGGACGACCCGGTTGTATCGCAGTTTCTGACTTTTCTCGAAAATGACATGAAGAAA
AACCCGCAGAACATTCACCCAGTACCGGTAATGTTTTGGGATAGCATGAAAGCACTGACTGCTGGAGTTGAGGTCGATTT
AGACGCGCCGCTTACCGATGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References