Detailed information of TA system TA113038

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2635816..2636141
• Replicon: chromosome
• Accession: NZ_CP033064
• Organism: Bacillus sp. WR11

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: D9C22_RS13845
• Protein ID: WP_128751232.1
• Coordinates: 2635816..2635995 (+)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2635919..2636141 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D9C22_RS13835	2635042..2635179	-	138	WP_021480099.1	hypothetical protein	-
D9C22_RS13840	2635221..2635670	-	450	WP_032722171.1	phage portal protein	-
D9C22_RS13845	2635816..2635995	+	180	WP_128751232.1	type I toxin-antitoxin system toxin TxpA	Toxin
-	2635919..2636141	-	223	NuclAT_0	-	Antitoxin
-	2635919..2636141	-	223	NuclAT_0	-	Antitoxin
-	2635919..2636141	-	223	NuclAT_0	-	Antitoxin
-	2635919..2636141	-	223	NuclAT_0	-	Antitoxin
D9C22_RS13850	2636375..2636464	+	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
D9C22_RS13855	2636718..2637161	-	444	WP_003229930.1	phage tail tube protein	-
D9C22_RS13860	2637164..2638564	-	1401	WP_003229929.1	phage tail sheath family protein	-
D9C22_RS13865	2638565..2638756	-	192	WP_010886574.1	hypothetical protein	-
D9C22_RS13870	2638753..2639190	-	438	WP_003229927.1	hypothetical protein	-
D9C22_RS13875	2639203..2639706	-	504	WP_003246050.1	HK97 gp10 family phage protein	-
D9C22_RS13880	2639703..2640065	-	363	WP_003229925.1	YqbH/XkdH family protein	-
D9C22_RS13885	2640062..2640457	-	396	WP_004398566.1	DUF3199 family protein	-
D9C22_RS13890	2640461..2640772	-	312	WP_003229923.1	YqbF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2603063..2656819	53756

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-122)

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6755.19 Da
• Isoelectric Point: 8.0288

>T113038 WP_128751232.1 NZ_CP033064:2635816-2635995 [Bacillus sp. WR11]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLYMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T113038 NZ_CP033064:2635816-2635995 [Bacillus sp. WR11]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATACATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin

Nucleotide

• Length: 223 bp

>AT113038 NZ_CP033064:c2636141-2635919 [Bacillus sp. WR11]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Antitoxin