Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-as-bsrH/-
Location 2185280..2185497 Replicon chromosome
Accession NZ_CP033064
Organism Bacillus sp. WR11

Toxin (Protein)


Gene name yonT Uniprot ID -
Locus tag D9C22_RS11255 Protein ID WP_019712271.1
Coordinates 2185280..2185456 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrH
Locus tag -
Coordinates 2185397..2185497 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D9C22_RS11220 2181157..2181378 - 222 WP_128751206.1 hypothetical protein -
D9C22_RS11225 2181375..2181776 - 402 WP_128751207.1 hypothetical protein -
D9C22_RS11230 2181822..2182259 - 438 WP_128751208.1 hypothetical protein -
D9C22_RS11235 2182575..2183792 - 1218 WP_128751209.1 hypothetical protein -
D9C22_RS11240 2183811..2184656 - 846 WP_128751210.1 GIY-YIG nuclease family protein -
D9C22_RS11245 2184777..2184965 - 189 WP_128751211.1 hypothetical protein -
D9C22_RS11250 2185010..2185261 - 252 WP_080010576.1 hypothetical protein -
D9C22_RS11255 2185280..2185456 - 177 WP_019712271.1 hypothetical protein Toxin
- 2185397..2185497 + 101 NuclAT_1 - Antitoxin
- 2185397..2185497 + 101 NuclAT_1 - Antitoxin
- 2185397..2185497 + 101 NuclAT_1 - Antitoxin
- 2185397..2185497 + 101 NuclAT_1 - Antitoxin
D9C22_RS11265 2185997..2186608 - 612 WP_074794693.1 hypothetical protein -
D9C22_RS11270 2186809..2187138 - 330 WP_032721651.1 helix-turn-helix domain-containing protein -
D9C22_RS11275 2188093..2188287 + 195 WP_072692657.1 hypothetical protein -
D9C22_RS11280 2188327..2190201 + 1875 Protein_2149 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2116100..2247070 130970


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 59 a.a.        Molecular weight: 6864.42 Da        Isoelectric Point: 12.8833

>T113034 WP_019712271.1 NZ_CP033064:c2185456-2185280 [Bacillus sp. WR11]
VLEKVGIIVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp

>T113034 NZ_CP033064:c2185456-2185280 [Bacillus sp. WR11]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTTCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 101 bp

>AT113034 NZ_CP033064:2185397-2185497 [Bacillus sp. WR11]
GATTGTAAGAACCGTTAAAGATATGAGAAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References