Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1661492..1662012 Replicon chromosome
Accession NZ_CP033034
Organism Agrobacterium fabrum strain 12D13

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag At12D13_RS08595 Protein ID WP_080808022.1
Coordinates 1661492..1661761 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag At12D13_RS08600 Protein ID WP_080808019.1
Coordinates 1661758..1662012 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
At12D13_RS08570 1656527..1658221 - 1695 WP_121690470.1 iron ABC transporter permease -
At12D13_RS08575 1658231..1659214 - 984 WP_121690471.1 ABC transporter substrate-binding protein -
At12D13_RS08585 1659519..1660763 - 1245 WP_092771028.1 PLP-dependent aminotransferase family protein -
At12D13_RS08590 1661038..1661487 + 450 WP_121690472.1 RbsD/FucU family protein -
At12D13_RS08595 1661492..1661761 - 270 WP_080808022.1 Txe/YoeB family addiction module toxin Toxin
At12D13_RS08600 1661758..1662012 - 255 WP_080808019.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
At12D13_RS08605 1662151..1663170 - 1020 WP_006311843.1 ketol-acid reductoisomerase -
At12D13_RS08610 1663218..1663871 - 654 WP_121690473.1 TetR/AcrR family transcriptional regulator -
At12D13_RS08615 1664269..1665174 - 906 WP_006311840.1 AraC family transcriptional regulator -
At12D13_RS08620 1665364..1666410 + 1047 WP_080808012.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10611.15 Da        Isoelectric Point: 9.8742

>T112985 WP_080808022.1 NZ_CP033034:c1661761-1661492 [Agrobacterium fabrum]
MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRITAEHRFVYRVSGSGSEQRLE
IIQCRFHYL

Download         Length: 270 bp

>T112985 NZ_CP033034:c1661761-1661492 [Agrobacterium fabrum]
ATGAAGCTCGTCTGGACGCTGAGTTCATGGGACGATTATGAGTTCTGGCAAAGAACCGATGCTCGCATGGTCGAGAAAAT
AAACGATCTTATCCGAAATGCCAAACGCACGCCCTTTGCAGGGCTTGGGAAACCGGAGCCTCTGAAGGGCGATATGGCAG
GATATTGGTCTCGGCGGATTACCGCCGAGCATCGGTTTGTCTACCGTGTATCCGGGTCCGGAAGCGAGCAACGGCTGGAA
ATCATCCAGTGTCGCTTTCACTACCTGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9692.84 Da        Isoelectric Point: 4.6882

>AT112985 WP_080808019.1 NZ_CP033034:c1662012-1661758 [Agrobacterium fabrum]
MANVRFTEFRQNFATHFDRVLETRAPLLVTRQGKEAVVVLAEGEYESMQETLHLLSNPANASRLRASMDELERDDTIERD
PTEK

Download         Length: 255 bp

>AT112985 NZ_CP033034:c1662012-1661758 [Agrobacterium fabrum]
ATGGCGAATGTGCGATTCACCGAGTTCCGGCAGAACTTCGCGACCCATTTCGACCGGGTTCTGGAAACCCGCGCGCCATT
GCTCGTCACGCGGCAGGGTAAAGAGGCGGTCGTGGTGCTCGCCGAAGGGGAATATGAGAGCATGCAGGAAACGCTGCATC
TCCTGTCCAACCCGGCAAATGCCTCACGGCTTCGCGCGTCCATGGACGAACTTGAGCGCGATGATACGATAGAGCGGGAT
CCGACCGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References