Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2191980..2192160 Replicon chromosome
Accession NZ_CP032821
Organism Staphylococcus aureus strain JDFM SA01

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag D5S13_RS11015 Protein ID WP_001801861.1
Coordinates 2192065..2192160 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2191980..2192037 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D5S13_RS10985 (D5S13_02098) 2188331..2189449 + 1119 WP_000072558.1 restriction endonuclease subunit S -
D5S13_RS10990 (D5S13_02099) 2190097..2190540 + 444 WP_000742594.1 DUF1433 domain-containing protein -
D5S13_RS10995 (D5S13_02100) 2190819..2191097 + 279 WP_001798632.1 DUF1433 domain-containing protein -
D5S13_RS11000 (D5S13_02101) 2191119..2191493 + 375 WP_000695818.1 DUF1433 domain-containing protein -
D5S13_RS11005 2191681..2191863 + 183 Protein_2120 transposase -
D5S13_RS11010 2191841..2191942 - 102 WP_001791232.1 hypothetical protein -
- 2191980..2192037 + 58 - - Antitoxin
D5S13_RS11015 2192065..2192160 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
D5S13_RS11020 (D5S13_02102) 2192611..2193057 + 447 WP_000747802.1 DUF1433 domain-containing protein -
D5S13_RS11025 (D5S13_02103) 2193742..2194125 + 384 WP_000070811.1 hypothetical protein -
D5S13_RS11030 (D5S13_02104) 2194136..2194312 + 177 WP_000375476.1 hypothetical protein -
D5S13_RS11035 (D5S13_02105) 2194612..2195240 + 629 Protein_2126 ImmA/IrrE family metallo-endopeptidase -
D5S13_RS11040 2195438..2196010 - 573 Protein_2127 hypothetical protein -
D5S13_RS11045 (D5S13_02108) 2196111..2196452 - 342 WP_000627548.1 DUF3969 family protein -
D5S13_RS11050 (D5S13_02109) 2196493..2197119 - 627 WP_000669019.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - hlgA / lukD 2142575..2198885 56310


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T112594 WP_001801861.1 NZ_CP032821:c2192160-2192065 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T112594 NZ_CP032821:c2192160-2192065 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT112594 NZ_CP032821:2191980-2192037 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References