Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1899532..1899810 Replicon chromosome
Accession NZ_CP032821
Organism Staphylococcus aureus strain JDFM SA01

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag D5S13_RS09320 Protein ID WP_001802298.1
Coordinates 1899532..1899636 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1899632..1899810 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D5S13_RS09305 (D5S13_01782) 1896329..1897111 + 783 WP_000908189.1 ABC transporter ATP-binding protein -
D5S13_RS09310 (D5S13_01783) 1897179..1898036 + 858 WP_000370928.1 HAD family hydrolase -
D5S13_RS09315 1898694..1898852 - 159 WP_001792784.1 hypothetical protein -
D5S13_RS09320 1899532..1899636 + 105 WP_001802298.1 hypothetical protein Toxin
- 1899632..1899810 - 179 - - Antitoxin
D5S13_RS09330 (D5S13_01784) 1900078..1901169 - 1092 WP_000495681.1 hypothetical protein -
D5S13_RS09335 (D5S13_01785) 1901435..1902415 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
D5S13_RS09340 (D5S13_01786) 1902417..1902737 - 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
D5S13_RS09345 (D5S13_01787) 1902889..1903554 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T112587 WP_001802298.1 NZ_CP032821:1899532-1899636 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T112587 NZ_CP032821:1899532-1899636 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT112587 NZ_CP032821:c1899810-1899632 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9


Antitoxin

Download structure file

References