Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 1899532..1899794 | Replicon | chromosome |
Accession | NZ_CP032821 | ||
Organism | Staphylococcus aureus strain JDFM SA01 |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | Q2FWA7 |
Locus tag | D5S13_RS09320 | Protein ID | WP_001802298.1 |
Coordinates | 1899532..1899636 (+) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF2 | ||
Locus tag | - | ||
Coordinates | 1899631..1899794 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D5S13_RS09305 (D5S13_01782) | 1896329..1897111 | + | 783 | WP_000908189.1 | ABC transporter ATP-binding protein | - |
D5S13_RS09310 (D5S13_01783) | 1897179..1898036 | + | 858 | WP_000370928.1 | HAD family hydrolase | - |
D5S13_RS09315 | 1898694..1898852 | - | 159 | WP_001792784.1 | hypothetical protein | - |
D5S13_RS09320 | 1899532..1899636 | + | 105 | WP_001802298.1 | hypothetical protein | Toxin |
- | 1899631..1899794 | - | 164 | - | - | Antitoxin |
D5S13_RS09330 (D5S13_01784) | 1900078..1901169 | - | 1092 | WP_000495681.1 | hypothetical protein | - |
D5S13_RS09335 (D5S13_01785) | 1901435..1902415 | - | 981 | WP_000019743.1 | CDF family zinc efflux transporter CzrB | - |
D5S13_RS09340 (D5S13_01786) | 1902417..1902737 | - | 321 | WP_000003755.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
D5S13_RS09345 (D5S13_01787) | 1902889..1903554 | + | 666 | WP_001024095.1 | SDR family oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T112586 WP_001802298.1 NZ_CP032821:1899532-1899636 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T112586 NZ_CP032821:1899532-1899636 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
Antitoxin
Download Length: 164 bp
>AT112586 NZ_CP032821:c1899794-1899631 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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