Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1621328..1621512 Replicon chromosome
Accession NZ_CP032821
Organism Staphylococcus aureus strain JDFM SA01

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag D5S13_RS07865 Protein ID WP_072467491.1
Coordinates 1621328..1621435 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1621452..1621512 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D5S13_RS07840 (D5S13_01505) 1616701..1617174 + 474 WP_000456489.1 GyrI-like domain-containing protein -
D5S13_RS07845 (D5S13_01506) 1617297..1618508 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
D5S13_RS07850 (D5S13_01507) 1618690..1619349 - 660 WP_000831298.1 membrane protein -
D5S13_RS07855 (D5S13_01508) 1619409..1620551 - 1143 WP_001176873.1 glycerate kinase -
D5S13_RS07860 (D5S13_01509) 1620808..1621194 + 387 WP_000779348.1 flippase GtxA -
D5S13_RS07865 1621328..1621435 + 108 WP_072467491.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1621452..1621512 - 61 - - Antitoxin
D5S13_RS07870 (D5S13_01510) 1622025..1623788 + 1764 WP_001064834.1 ABC transporter ATP-binding protein -
D5S13_RS07875 (D5S13_01511) 1623813..1625546 + 1734 WP_000486502.1 ABC transporter ATP-binding protein -
D5S13_RS07880 1625777..1625944 + 168 WP_031866196.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3944.67 Da        Isoelectric Point: 10.4934

>T112583 WP_072467491.1 NZ_CP032821:1621328-1621435 [Staphylococcus aureus]
IFNLLIDIMTSAISGCLVAFFANWLRTRSNKKGDK

Download         Length: 108 bp

>T112583 NZ_CP032821:1621328-1621435 [Staphylococcus aureus]
ATCTTCAATTTATTAATTGACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCAAATTGGTTACGAAC
GCGCAGCAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT112583 NZ_CP032821:c1621512-1621452 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References