Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2669996..2670530 Replicon chromosome
Accession NZ_CP032689
Organism Rhizobium sp. CCGE532

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CCGE532_RS13170 Protein ID WP_120664660.1
Coordinates 2669996..2670262 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CCGE532_RS13175 Protein ID WP_120664661.1
Coordinates 2670270..2670530 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE532_RS13145 2665260..2666498 + 1239 WP_120664655.1 urate hydroxylase PuuD -
CCGE532_RS13150 2666495..2667802 + 1308 WP_120664656.1 guanine deaminase -
CCGE532_RS13155 2667834..2668154 + 321 WP_120664657.1 type II toxin-antitoxin system HigB family toxin -
CCGE532_RS13160 2668147..2668578 + 432 WP_120664658.1 DUF1508 domain-containing protein -
CCGE532_RS13165 2668747..2669886 + 1140 WP_120664659.1 alpha-hydroxy-acid oxidizing protein -
CCGE532_RS13170 2669996..2670262 - 267 WP_120664660.1 Txe/YoeB family addiction module toxin Toxin
CCGE532_RS13175 2670270..2670530 - 261 WP_120664661.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CCGE532_RS13180 2670598..2671338 - 741 WP_120664662.1 metallophosphatase family protein -
CCGE532_RS13185 2671342..2671698 - 357 WP_120664663.1 hydroxyisourate hydrolase -
CCGE532_RS13190 2671695..2672195 - 501 WP_120664664.1 ureidoglycolate lyase -
CCGE532_RS13195 2672203..2672565 - 363 WP_120664665.1 DUF86 domain-containing protein -
CCGE532_RS13200 2672626..2673123 - 498 WP_120664666.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
CCGE532_RS13205 2673125..2674048 - 924 WP_120664667.1 allantoinase PuuE -
CCGE532_RS13210 2674154..2674861 - 708 WP_120664668.1 DUF1045 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10738.31 Da        Isoelectric Point: 9.5457

>T112152 WP_120664660.1 NZ_CP032689:c2670262-2669996 [Rhizobium sp. CCGE532]
MLLAWHGHAWEDYLYWQEKDRKVVARISELLRDALRHPFEGLGKPEPLRNQLKGQWSRRITQEHRLIYRVEGEGDRQTLI
VLQCRFHY

Download         Length: 267 bp

>T112152 NZ_CP032689:c2670262-2669996 [Rhizobium sp. CCGE532]
ATGTTGCTTGCCTGGCATGGACACGCTTGGGAAGACTATCTCTATTGGCAGGAAAAAGACCGAAAAGTAGTTGCTAGGAT
CAGCGAACTCCTGCGGGATGCCCTGCGTCACCCTTTCGAGGGACTCGGCAAGCCGGAGCCTCTGCGCAATCAGCTCAAAG
GCCAGTGGTCACGTCGCATTACGCAAGAGCATAGGCTGATTTACAGGGTTGAGGGTGAAGGGGATCGGCAAACACTTATC
GTCCTGCAATGTCGCTTCCACTACTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9570.91 Da        Isoelectric Point: 4.4978

>AT112152 WP_120664661.1 NZ_CP032689:c2670530-2670270 [Rhizobium sp. CCGE532]
MRTVMFSTARNELASLLDEVAQDRVAVEIVRRDKPSAILIDKDEYEGMMETLHALSTPANAARLMEAIADANEGRNLVSR
DLLDPK

Download         Length: 261 bp

>AT112152 NZ_CP032689:c2670530-2670270 [Rhizobium sp. CCGE532]
ATGCGAACAGTCATGTTTTCAACAGCCCGCAATGAACTCGCAAGCCTGCTCGATGAGGTCGCGCAGGACCGTGTTGCCGT
GGAAATCGTGCGTCGTGACAAGCCATCGGCCATTCTGATCGACAAGGACGAATATGAAGGGATGATGGAGACGCTTCATG
CCCTGTCGACGCCGGCCAATGCGGCGCGGTTGATGGAAGCGATCGCTGACGCGAACGAGGGGAGGAACCTCGTCTCTCGC
GATCTGCTTGATCCGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References