Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2815876..2816410 Replicon chromosome
Accession NZ_CP032684
Organism Rhizobium sp. CCGE531

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CCGE531_RS13745 Protein ID WP_120664660.1
Coordinates 2815876..2816142 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CCGE531_RS13750 Protein ID WP_120664661.1
Coordinates 2816150..2816410 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCGE531_RS13720 2811140..2812378 + 1239 WP_120664655.1 urate hydroxylase PuuD -
CCGE531_RS13725 2812375..2813682 + 1308 WP_120664656.1 guanine deaminase -
CCGE531_RS13730 2813714..2814034 + 321 WP_120664657.1 type II toxin-antitoxin system HigB family toxin -
CCGE531_RS13735 2814027..2814458 + 432 WP_120664658.1 DUF1508 domain-containing protein -
CCGE531_RS13740 2814627..2815766 + 1140 WP_120664659.1 alpha-hydroxy-acid oxidizing protein -
CCGE531_RS13745 2815876..2816142 - 267 WP_120664660.1 Txe/YoeB family addiction module toxin Toxin
CCGE531_RS13750 2816150..2816410 - 261 WP_120664661.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CCGE531_RS13755 2816478..2817218 - 741 WP_120664662.1 metallophosphatase family protein -
CCGE531_RS13760 2817222..2817578 - 357 WP_120664663.1 hydroxyisourate hydrolase -
CCGE531_RS13765 2817575..2818075 - 501 WP_120664664.1 ureidoglycolate lyase -
CCGE531_RS13770 2818083..2818445 - 363 WP_120664665.1 DUF86 domain-containing protein -
CCGE531_RS13775 2818506..2819003 - 498 WP_120664666.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
CCGE531_RS13780 2819005..2819928 - 924 WP_120664667.1 allantoinase PuuE -
CCGE531_RS13785 2820034..2820741 - 708 WP_120664668.1 DUF1045 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10738.31 Da        Isoelectric Point: 9.5457

>T112141 WP_120664660.1 NZ_CP032684:c2816142-2815876 [Rhizobium sp. CCGE531]
MLLAWHGHAWEDYLYWQEKDRKVVARISELLRDALRHPFEGLGKPEPLRNQLKGQWSRRITQEHRLIYRVEGEGDRQTLI
VLQCRFHY

Download         Length: 267 bp

>T112141 NZ_CP032684:c2816142-2815876 [Rhizobium sp. CCGE531]
ATGTTGCTTGCCTGGCATGGACACGCTTGGGAAGACTATCTCTATTGGCAGGAAAAAGACCGAAAAGTAGTTGCTAGGAT
CAGCGAACTCCTGCGGGATGCCCTGCGTCACCCTTTCGAGGGACTCGGCAAGCCGGAGCCTCTGCGCAATCAGCTCAAAG
GCCAGTGGTCACGTCGCATTACGCAAGAGCATAGGCTGATTTACAGGGTTGAGGGTGAAGGGGATCGGCAAACACTTATC
GTCCTGCAATGTCGCTTCCACTACTAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9570.91 Da        Isoelectric Point: 4.4978

>AT112141 WP_120664661.1 NZ_CP032684:c2816410-2816150 [Rhizobium sp. CCGE531]
MRTVMFSTARNELASLLDEVAQDRVAVEIVRRDKPSAILIDKDEYEGMMETLHALSTPANAARLMEAIADANEGRNLVSR
DLLDPK

Download         Length: 261 bp

>AT112141 NZ_CP032684:c2816410-2816150 [Rhizobium sp. CCGE531]
ATGCGAACAGTCATGTTTTCAACAGCCCGCAATGAACTCGCAAGCCTGCTCGATGAGGTCGCGCAGGACCGTGTTGCCGT
GGAAATCGTGCGTCGTGACAAGCCATCGGCCATTCTGATCGACAAGGACGAATATGAAGGGATGATGGAGACGCTTCATG
CCCTGTCGACGCCGGCCAATGCGGCGCGGTTGATGGAAGCGATCGCTGACGCGAACGAGGGGAGGAACCTCGTCTCTCGC
GATCTGCTTGATCCGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References