Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3055216..3055718 Replicon chromosome
Accession NZ_CP032619
Organism Pectobacterium carotovorum strain HG-49

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7W2E5L4
Locus tag D7Z95_RS13805 Protein ID WP_039282578.1
Coordinates 3055216..3055470 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag D7Z95_RS13810 Protein ID WP_039324900.1
Coordinates 3055467..3055718 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7Z95_RS13785 3050353..3051615 - 1263 WP_205947166.1 L-rhamnose isomerase -
D7Z95_RS13790 3051612..3053102 - 1491 WP_205947165.1 rhamnulokinase -
D7Z95_RS13795 3053438..3054277 + 840 WP_205947164.1 HTH-type transcriptional activator RhaS -
D7Z95_RS13800 3054302..3055156 + 855 WP_205947163.1 helix-turn-helix domain-containing protein -
D7Z95_RS13805 3055216..3055470 - 255 WP_039282578.1 Txe/YoeB family addiction module toxin Toxin
D7Z95_RS13810 3055467..3055718 - 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
D7Z95_RS13815 3055794..3057503 - 1710 WP_205947162.1 ABC transporter ATP-binding protein -
D7Z95_RS13820 3057500..3058366 - 867 WP_010285293.1 ABC transporter permease -
D7Z95_RS13825 3058359..3059318 - 960 WP_012773138.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10229.79 Da        Isoelectric Point: 8.0353

>T112015 WP_039282578.1 NZ_CP032619:c3055470-3055216 [Pectobacterium carotovorum]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

>T112015 NZ_CP032619:c3055470-3055216 [Pectobacterium carotovorum]
GTGAAGCTAATCTGGTCAGAAGAAGCATGGGAAGACTACCTGTACTGGCAGGACATCGATAAGCGGATGGTCAAAAAGAT
CAATGAATTAATAAAAGAAACGCGTAGAACACCTTTTGAGGGAAAAGGAAAACCGGAGCCACTTAAACATAACCTCGCTG
GTTTCTGGTCGCGCCGTATAACCGAAGAGCATCGTCTGGTCTATGCCATCACCGATGACGCCATGATGATCGCTGCCTGC
CGCTACCACTATTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT112015 WP_039324900.1 NZ_CP032619:c3055718-3055467 [Pectobacterium carotovorum]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp

>AT112015 NZ_CP032619:c3055718-3055467 [Pectobacterium carotovorum]
ATGCGTACAATTAGCTACAGTGAAGCCCGACAAAATCTATCGGCGACCATGATGAAAACGGTCGAAGACCGTGCTCCCAT
TCTTATCACTCGACAGAATGGTGAAGCCTGCGTGCTCATGTCTTTGGAAGAATATAACTCTCTAGAGGAGACCGCGTATT
TACTGCGTTCACCAGCAAATGCAAAAAGACTGATGAACTCAATCGAGAGCCTTAAAGCTGGCAATGGCGAAGAAAGAGAT
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E5L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References