Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 97957..98614 | Replicon | plasmid pSDU1-USMARC-69838 |
| Accession | NZ_CP032450 | ||
| Organism | Salmonella enterica subsp. enterica serovar Dublin strain USMARC-69838 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | DZA56_RS25845 | Protein ID | WP_000270043.1 |
| Coordinates | 97957..98307 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | DZA56_RS25850 | Protein ID | WP_000124640.1 |
| Coordinates | 98312..98614 (+) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DZA56_RS25790 | 92987..93451 | - | 465 | Protein_112 | recombinase family protein | - |
| DZA56_RS25795 | 93512..94216 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| DZA56_RS25805 | 94431..94928 | - | 498 | WP_000062185.1 | hypothetical protein | - |
| DZA56_RS25810 | 94931..95419 | - | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| DZA56_RS25815 | 95516..95851 | + | 336 | WP_000683476.1 | hypothetical protein | - |
| DZA56_RS25820 | 95866..96336 | - | 471 | WP_001281821.1 | hypothetical protein | - |
| DZA56_RS25825 | 96329..96700 | - | 372 | WP_000516916.1 | hypothetical protein | - |
| DZA56_RS25830 | 96711..96905 | - | 195 | WP_000343597.1 | hypothetical protein | - |
| DZA56_RS26190 | 96933..97124 | + | 192 | WP_014342197.1 | hypothetical protein | - |
| DZA56_RS25840 | 97246..97794 | - | 549 | WP_001061574.1 | transcriptional regulator | - |
| DZA56_RS25845 | 97957..98307 | + | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| DZA56_RS25850 | 98312..98614 | + | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| DZA56_RS25855 | 98641..98934 | - | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
| DZA56_RS25860 | 99022..99294 | - | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
| DZA56_RS25865 | 99352..99879 | - | 528 | WP_001236377.1 | thermonuclease family protein | - |
| DZA56_RS25870 | 99896..100042 | - | 147 | WP_014342196.1 | hypothetical protein | - |
| DZA56_RS25875 | 100110..100967 | - | 858 | WP_001167032.1 | hypothetical protein | - |
| DZA56_RS25880 | 100954..101184 | - | 231 | WP_000972663.1 | hypothetical protein | - |
| DZA56_RS25885 | 101184..101702 | - | 519 | WP_000210756.1 | nitrite reductase | - |
| DZA56_RS25890 | 101699..102145 | - | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| DZA56_RS25895 | 102145..102504 | - | 360 | WP_000422768.1 | hypothetical protein | - |
| DZA56_RS25900 | 102561..102989 | - | 429 | WP_000591074.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..114923 | 114923 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 15014.38 Da Isoelectric Point: 12.8644
>T111805 WP_000270043.1 NZ_CP032450:97957-98307 [Salmonella enterica subsp. enterica serovar Dublin]
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Download Length: 351 bp
>T111805 NZ_CP032450:97957-98307 [Salmonella enterica subsp. enterica serovar Dublin]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 12963.60 Da Isoelectric Point: 12.8000
>AT111805 WP_000124640.1 NZ_CP032450:98312-98614 [Salmonella enterica subsp. enterica serovar Dublin]
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Download Length: 303 bp
>AT111805 NZ_CP032450:98312-98614 [Salmonella enterica subsp. enterica serovar Dublin]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|