Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 1631..2288 | Replicon | plasmid p22453_1 |
Accession | NZ_CP032395 | ||
Organism | Salmonella enterica subsp. enterica serovar Dublin strain CVM 22453 |
Toxin (Protein)
Gene name | higB | Uniprot ID | U3PDC3 |
Locus tag | D5G00_RS25215 | Protein ID | WP_000270043.1 |
Coordinates | 1631..1981 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | D5G00_RS25220 | Protein ID | WP_000124640.1 |
Coordinates | 1986..2288 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D5G00_RS25195 | 3..374 | - | 372 | WP_000516916.1 | hypothetical protein | - |
D5G00_RS25200 | 385..579 | - | 195 | WP_000343597.1 | hypothetical protein | - |
D5G00_RS25210 | 920..1468 | - | 549 | WP_001061574.1 | transcriptional regulator | - |
D5G00_RS25215 | 1631..1981 | + | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
D5G00_RS25220 | 1986..2288 | + | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
D5G00_RS25225 | 2315..2608 | - | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
D5G00_RS25230 | 2696..2968 | - | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
D5G00_RS25235 | 3026..3553 | - | 528 | WP_001236377.1 | thermonuclease family protein | - |
D5G00_RS25245 | 3784..4641 | - | 858 | WP_001167032.1 | hypothetical protein | - |
D5G00_RS25250 | 4628..4858 | - | 231 | WP_000972663.1 | hypothetical protein | - |
D5G00_RS25255 | 4858..5376 | - | 519 | WP_000210756.1 | nitrite reductase | - |
D5G00_RS25260 | 5373..5819 | - | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
D5G00_RS25265 | 5819..6178 | - | 360 | Protein_12 | hypothetical protein | - |
D5G00_RS25270 | 6235..6663 | - | 429 | WP_000591074.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..164900 | 164900 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 15014.38 Da Isoelectric Point: 12.8644
>T111733 WP_000270043.1 NZ_CP032395:1631-1981 [Salmonella enterica subsp. enterica serovar Dublin]
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Download Length: 351 bp
>T111733 NZ_CP032395:1631-1981 [Salmonella enterica subsp. enterica serovar Dublin]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 12963.60 Da Isoelectric Point: 12.8000
>AT111733 WP_000124640.1 NZ_CP032395:1986-2288 [Salmonella enterica subsp. enterica serovar Dublin]
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Download Length: 303 bp
>AT111733 NZ_CP032395:1986-2288 [Salmonella enterica subsp. enterica serovar Dublin]
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Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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