Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 102635..103292 | Replicon | plasmid pN45955_1 |
| Accession | NZ_CP032388 | ||
| Organism | Salmonella enterica subsp. enterica serovar Dublin strain CVM N45955 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | D5F98_RS25460 | Protein ID | WP_000270043.1 |
| Coordinates | 102942..103292 (-) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | D5F98_RS25455 | Protein ID | WP_000124640.1 |
| Coordinates | 102635..102937 (-) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D5F98_RS25405 | 98260..98688 | + | 429 | WP_000591074.1 | hypothetical protein | - |
| D5F98_RS25410 | 98745..99104 | + | 360 | WP_000422768.1 | hypothetical protein | - |
| D5F98_RS25415 | 99104..99550 | + | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| D5F98_RS25420 | 99547..100065 | + | 519 | WP_000210756.1 | nitrite reductase | - |
| D5F98_RS25425 | 100065..100295 | + | 231 | WP_000972663.1 | hypothetical protein | - |
| D5F98_RS25430 | 100282..101139 | + | 858 | WP_001167032.1 | hypothetical protein | - |
| D5F98_RS25440 | 101370..101897 | + | 528 | WP_001236377.1 | thermonuclease family protein | - |
| D5F98_RS25445 | 101955..102227 | + | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
| D5F98_RS25450 | 102315..102608 | + | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
| D5F98_RS25455 | 102635..102937 | - | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| D5F98_RS25460 | 102942..103292 | - | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| D5F98_RS25465 | 103455..104003 | + | 549 | WP_001061574.1 | transcriptional regulator | - |
| D5F98_RS25475 | 104344..104538 | + | 195 | WP_000343597.1 | hypothetical protein | - |
| D5F98_RS25480 | 104549..104920 | + | 372 | WP_000516916.1 | hypothetical protein | - |
| D5F98_RS25485 | 104913..105383 | + | 471 | WP_001281821.1 | hypothetical protein | - |
| D5F98_RS25490 | 105398..105733 | - | 336 | WP_000683476.1 | hypothetical protein | - |
| D5F98_RS25495 | 105830..106318 | + | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| D5F98_RS25500 | 106321..106818 | + | 498 | WP_000062185.1 | hypothetical protein | - |
| D5F98_RS25505 | 107033..107737 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| D5F98_RS25510 | 107802..107981 | - | 180 | Protein_135 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..124532 | 124532 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 17237.68 Da Isoelectric Point: 5.5500
>T111724 WP_000270043.1 NZ_CP032388:c103292-102942 [Salmonella enterica subsp. enterica serovar Dublin]
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FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
Download Length: 351 bp
>T111724 NZ_CP032388:c103292-102942 [Salmonella enterica subsp. enterica serovar Dublin]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 14882.85 Da Isoelectric Point: 5.5500
>AT111724 WP_000124640.1 NZ_CP032388:c102937-102635 [Salmonella enterica subsp. enterica serovar Dublin]
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Download Length: 303 bp
>AT111724 NZ_CP032388:c102937-102635 [Salmonella enterica subsp. enterica serovar Dublin]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|