Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 75473..76130 | Replicon | plasmid pN53043_1 |
| Accession | NZ_CP032385 | ||
| Organism | Salmonella enterica subsp. enterica serovar Dublin strain CVM N53043 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | D5F97_RS25445 | Protein ID | WP_000270043.1 |
| Coordinates | 75473..75823 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | D5F97_RS25450 | Protein ID | WP_000124640.1 |
| Coordinates | 75828..76130 (+) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D5F97_RS25395 | 70784..70963 | + | 180 | Protein_86 | helix-turn-helix transcriptional regulator | - |
| D5F97_RS25400 | 71028..71732 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| D5F97_RS25405 | 71947..72444 | - | 498 | WP_000062185.1 | hypothetical protein | - |
| D5F97_RS25410 | 72447..72935 | - | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| D5F97_RS25415 | 73032..73367 | + | 336 | WP_000683476.1 | hypothetical protein | - |
| D5F97_RS25420 | 73382..73852 | - | 471 | WP_001281821.1 | hypothetical protein | - |
| D5F97_RS25425 | 73845..74216 | - | 372 | WP_000516916.1 | hypothetical protein | - |
| D5F97_RS25430 | 74227..74421 | - | 195 | WP_000343597.1 | hypothetical protein | - |
| D5F97_RS25440 | 74762..75310 | - | 549 | WP_001061574.1 | transcriptional regulator | - |
| D5F97_RS25445 | 75473..75823 | + | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| D5F97_RS25450 | 75828..76130 | + | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| D5F97_RS25455 | 76157..76450 | - | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
| D5F97_RS25460 | 76538..76810 | - | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
| D5F97_RS25465 | 76868..77395 | - | 528 | WP_001236377.1 | thermonuclease family protein | - |
| D5F97_RS25475 | 77626..78483 | - | 858 | WP_001167032.1 | hypothetical protein | - |
| D5F97_RS25480 | 78470..78700 | - | 231 | WP_000972663.1 | hypothetical protein | - |
| D5F97_RS25485 | 78700..79218 | - | 519 | WP_000210756.1 | nitrite reductase | - |
| D5F97_RS25490 | 79215..79661 | - | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| D5F97_RS25495 | 79661..80020 | - | 360 | WP_000422768.1 | hypothetical protein | - |
| D5F97_RS25500 | 80077..80505 | - | 429 | WP_000591074.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..103514 | 103514 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 15014.38 Da Isoelectric Point: 12.8644
>T111718 WP_000270043.1 NZ_CP032385:75473-75823 [Salmonella enterica subsp. enterica serovar Dublin]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
Download Length: 351 bp
>T111718 NZ_CP032385:75473-75823 [Salmonella enterica subsp. enterica serovar Dublin]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Antitoxin
Download Length: 101 a.a. Molecular weight: 12963.60 Da Isoelectric Point: 12.8000
>AT111718 WP_000124640.1 NZ_CP032385:75828-76130 [Salmonella enterica subsp. enterica serovar Dublin]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKK
Download Length: 303 bp
>AT111718 NZ_CP032385:75828-76130 [Salmonella enterica subsp. enterica serovar Dublin]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|