111717

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 8044444..8045707 Replicon chromosome
Accession NZ_CP032382
Organism Chryseolinea soli strain KIS68-18

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag D4L85_RS33400 Protein ID WP_119758435.1
Coordinates 8044769..8045707 (+) Length 313 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag D4L85_RS33395 Protein ID WP_119758434.1
Coordinates 8044444..8044776 (+) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4L85_RS33365 8039670..8040197 - 528 WP_160144178.1 hypothetical protein -
D4L85_RS33375 8040434..8041198 + 765 WP_119759045.1 ThuA domain-containing protein -
D4L85_RS33380 8041429..8042397 + 969 WP_119758431.1 methylenetetrahydrofolate reductase -
D4L85_RS33385 8042608..8043711 - 1104 WP_119758432.1 DUF2911 domain-containing protein -
D4L85_RS33390 8044229..8044447 + 219 WP_119758433.1 helix-turn-helix transcriptional regulator -
D4L85_RS33395 8044444..8044776 + 333 WP_119758434.1 HipA N-terminal domain-containing protein Antitoxin
D4L85_RS33400 8044769..8045707 + 939 WP_119758435.1 HipA domain-containing protein Toxin
D4L85_RS33405 8045998..8046414 - 417 WP_119758436.1 Ohr family peroxiredoxin -
D4L85_RS33410 8046443..8047462 - 1020 WP_119758437.1 NAD(P)-dependent alcohol dehydrogenase -
D4L85_RS33415 8047532..8048506 + 975 WP_119758438.1 AraC family transcriptional regulator -
D4L85_RS33425 8049009..8049659 + 651 WP_119758440.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(55-274)

Antitoxin

HipA, N-terminal subdomain 1

(5-102)


Sequences

Toxin        


Download         Length: 313 a.a.        Molecular weight: 35511.04 Da        Isoelectric Point: 6.5077

>T111717 WP_119758435.1 NZ_CP032382:8044769-8045707 [Chryseolinea soli]
MNSRCLYCYEPLEKETDFHERCSLKFFGTKTAPALEYSLGEMAALAKNVVESSIAVPGVQPKLSLTMVGESNVGKRFTVV
GALGGSYILKPPSANYPEMPEDEHVTMRMAEAFGIQTVPSSLIRLKSGELAYISRRIDRRPDGTKIHMIDMFQITEAFDK
YRSSMERIGKAISEYATNTLLEQVIFFELSIFCFLTGNNDMHLKNFSMIKDGDEWKLSPAYDLLNVVIINPKDDEELALT
LEGKKKKLTYDNFIKLGKELGLNDRQIQGVFKRIETNKGKAVEWIEKSFLSTEMKEAYKEIVMERYDVLKTK

Download         Length: 939 bp

>T111717 NZ_CP032382:8044769-8045707 [Chryseolinea soli]
ATGAATAGCCGGTGCCTTTATTGTTACGAGCCCTTAGAAAAAGAAACTGATTTCCATGAGCGATGCAGCCTGAAATTCTT
CGGAACGAAAACCGCGCCTGCGTTGGAATATTCGCTCGGAGAAATGGCTGCCCTTGCCAAGAATGTCGTGGAAAGCAGCA
TCGCCGTTCCAGGGGTTCAGCCTAAACTCTCGCTTACCATGGTCGGTGAAAGCAATGTTGGAAAGCGGTTCACCGTTGTA
GGAGCGCTAGGCGGTTCGTACATACTAAAACCACCTTCAGCGAATTACCCTGAGATGCCGGAAGACGAGCACGTCACCAT
GCGCATGGCCGAAGCATTCGGTATACAAACCGTACCATCAAGTCTGATACGATTAAAGTCCGGCGAACTTGCCTATATCT
CCCGTCGCATTGACCGCCGGCCGGATGGAACCAAGATCCACATGATCGACATGTTTCAAATTACCGAGGCCTTCGACAAA
TACAGAAGCTCCATGGAGCGCATCGGTAAAGCCATTTCGGAATACGCCACCAATACACTCCTTGAGCAAGTGATCTTTTT
TGAGCTCAGTATCTTTTGCTTTCTGACCGGAAACAATGATATGCACTTAAAAAACTTCTCCATGATAAAGGATGGAGACG
AATGGAAACTTTCTCCGGCCTATGATCTCTTGAACGTTGTCATCATCAATCCAAAAGATGATGAGGAGCTGGCGCTCACC
TTGGAAGGAAAGAAGAAAAAATTGACCTACGACAATTTCATAAAATTGGGCAAAGAGCTAGGCTTAAATGACCGCCAGAT
TCAAGGCGTTTTCAAAAGAATAGAGACAAACAAAGGGAAAGCGGTGGAGTGGATCGAAAAATCTTTTTTGTCGACGGAGA
TGAAGGAAGCGTATAAGGAAATAGTGATGGAAAGGTATGATGTGCTCAAAACGAAATGA

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 12559.36 Da        Isoelectric Point: 4.4299

>AT111717 WP_119758434.1 NZ_CP032382:8044444-8044776 [Chryseolinea soli]
MRRGEIYYDTILAGILTETDDGEYTFTYDDDYIAKYPSQFLTFSMPVNKTVYRDKRLFPFFDGLIPEGWLLDIAAKSWKI
NPNDRMGLLLACCQNCIGAVSVQPIAGKNE

Download         Length: 333 bp

>AT111717 NZ_CP032382:8044444-8044776 [Chryseolinea soli]
ATGAGACGAGGAGAAATTTATTACGATACTATACTGGCAGGCATCCTGACGGAGACTGACGATGGCGAGTATACGTTCAC
TTATGATGATGACTACATCGCAAAATATCCAAGCCAGTTCTTAACCTTCTCCATGCCGGTAAACAAAACCGTCTATCGCG
ACAAAAGGTTATTTCCATTCTTCGACGGACTTATACCGGAAGGATGGCTACTGGACATCGCTGCGAAAAGTTGGAAGATC
AATCCCAATGACCGCATGGGGTTGCTCCTGGCGTGTTGCCAGAATTGCATCGGAGCGGTTAGTGTACAACCTATTGCTGG
AAAAAATGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References