Detailed information of TA system TA111616

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2069515..2069761
• Replicon: chromosome
• Accession: NZ_CP032310
• Organism: Bacillus subtilis strain WB800N

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: D3Z87_RS22425
• Protein ID: WP_109789044.1
• Coordinates: 2069515..2069607 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2069588..2069761 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D3Z87_RS10435	2064674..2065009	+	336	WP_009967409.1	hypothetical protein	-
D3Z87_RS10440	2065056..2068661	-	3606	WP_004399367.1	membrane protein	-
D3Z87_RS10445	2068894..2069226	-	333	WP_026009814.1	hypothetical protein	-
D3Z87_RS22425	2069515..2069607	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2069588..2069761	-	174	-	-	Antitoxin
D3Z87_RS10455	2069876..2070718	-	843	WP_003231327.1	hypothetical protein	-
D3Z87_RS10460	2070918..2071376	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
D3Z87_RS10465	2071386..2073188	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
D3Z87_RS10470	2073290..2073847	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2055500..2080726	25226

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T111616 WP_109789044.1 NZ_CP032310:2069515-2069607 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T111616 NZ_CP032310:2069515-2069607 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT111616 NZ_CP032310:c2069761-2069588 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin