Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 88352..89179 Replicon chromosome
Accession NZ_CP032296
Organism Rahnella aquatilis strain ZF7

Toxin (Protein)


Gene name yhaV Uniprot ID H8NM45
Locus tag D3Z09_RS00410 Protein ID WP_014411451.1
Coordinates 88352..88828 (-) Length 159 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A0H3F4N7
Locus tag D3Z09_RS00415 Protein ID WP_013573435.1
Coordinates 88835..89179 (-) Length 115 a.a.

Genomic Context

D3Z09_RS00385D3Z09_RS00390D3Z09_RS00395D3Z09_RS00400D3Z09_RS00410D3Z09_RS00415D3Z09_RS00420D3Z09_RS00425D3Z09_RS00430D3Z09_RS00435D3Z09_RS00440
Location: 83590..85035 (1446 bp)
Type: Others
Protein ID: WP_119261072.1
Location: 85106..85564 (459 bp)
Type: Others
Protein ID: WP_013573431.1
Location: 85699..86121 (423 bp)
Type: Others
Protein ID: WP_013573432.1
Location: 86393..88072 (1680 bp)
Type: Others
Protein ID: WP_013573433.1
Location: 88352..88828 (477 bp)
Type: Toxin
Protein ID: WP_014411451.1
Location: 88835..89179 (345 bp)
Type: Antitoxin
Protein ID: WP_013573435.1
Location: 89261..89422 (162 bp)
Type: Others
Protein ID: WP_071882947.1
Location: 89563..90942 (1380 bp)
Type: Others
Protein ID: WP_013573436.1
Location: 90962..91744 (783 bp)
Type: Others
Protein ID: WP_014411455.1
Location: 91744..92610 (867 bp)
Type: Others
Protein ID: WP_014411456.1
Location: 92603..93538 (936 bp)
Type: Others
Protein ID: WP_119261073.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D3Z09_RS0038583590..85035+1446WP_119261072.1alpha/beta hydrolase-
D3Z09_RS0039085106..85564+459WP_013573431.1MarR family transcriptional regulator-
D3Z09_RS0039585699..86121+423WP_013573432.1organic hydroperoxide resistance protein-
D3Z09_RS0040086393..88072+1680WP_013573433.1kdo(2)-lipid A phosphoethanolamine 7''-transferase-
D3Z09_RS0041088352..88828-477WP_014411451.1type II toxin-antitoxin system YhaV family toxinToxin
D3Z09_RS0041588835..89179-345WP_013573435.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
D3Z09_RS0042089261..89422-162WP_071882947.1type II toxin-antitoxin system RelE/ParE family toxin-
D3Z09_RS0042589563..90942-1380WP_013573436.1MmgE/PrpD family protein-
D3Z09_RS0043090962..91744-783WP_014411455.1ABC transporter ATP-binding protein-
D3Z09_RS0043591744..92610-867WP_014411456.1ABC transporter ATP-binding protein-
D3Z09_RS0044092603..93538-936WP_119261073.1ABC transporter permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(13-148)

Antitoxin

SpoVT-AbrB domain

(15-53)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 18482.31 Da        Isoelectric Point: 9.9550

>T111594 WP_014411451.1 NZ_CP032296:c88828-88352 [Rahnella aquatilis]
MHNQAMEINGWTLLAHPLILQQIQALTDQVVLLRRKDPAGYKSKNATKRLAAINKLMFDVIPQDPARVEFRQGDTLGGEF
SHWFRAKFFQQYRLFFRYNLKSRIIIYAWVNDDKELRAYESKTDAYRMFRKMLKSGEPPDNWQALCEASGKVAAEELP

Download         Length: 477 bp

>T111594 NZ_CP032296:c88828-88352 [Rahnella aquatilis]
ATGCACAATCAGGCCATGGAGATTAACGGATGGACCCTTCTCGCTCATCCTCTGATCCTGCAACAAATACAGGCACTCAC
TGATCAGGTTGTTTTACTGCGCCGCAAAGATCCGGCAGGCTATAAAAGTAAGAACGCCACCAAACGGCTGGCTGCGATCA
ATAAGCTGATGTTTGACGTTATCCCGCAGGATCCGGCGCGTGTTGAATTCCGTCAGGGCGATACGTTAGGCGGGGAATTC
TCACACTGGTTCAGGGCAAAATTCTTCCAGCAGTACCGTTTGTTTTTCCGCTACAATCTGAAAAGCCGGATCATTATTTA
CGCCTGGGTGAATGATGATAAAGAATTACGCGCCTACGAAAGCAAAACAGACGCATACCGGATGTTTCGCAAGATGTTGA
AAAGCGGTGAACCGCCAGACAACTGGCAGGCACTTTGCGAGGCGTCAGGGAAGGTAGCGGCGGAAGAATTACCTTAG

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12701.48 Da        Isoelectric Point: 4.3324

>AT111594 WP_013573435.1 NZ_CP032296:c89179-88835 [Rahnella aquatilis]
MSASALWGIKFEAESKVTRRFQTTIPATIRKALNLTENDRIQYKILPDGQVVISRQLEEAEDPVISAFLGFVAKDMLNNP
ENMQPVTLSLHEKINVLTAGMAIDLESPLSDDDE

Download         Length: 345 bp

>AT111594 NZ_CP032296:c89179-88835 [Rahnella aquatilis]
ATGTCAGCCTCGGCACTATGGGGAATAAAATTCGAAGCCGAATCCAAAGTCACCCGCCGCTTCCAGACCACCATTCCGGC
CACTATCCGTAAGGCATTAAATCTCACCGAAAATGATCGGATCCAGTACAAGATTTTGCCAGACGGGCAGGTGGTTATTT
CGAGGCAACTCGAAGAAGCGGAAGACCCTGTTATCAGTGCTTTTCTCGGTTTTGTGGCAAAAGATATGCTCAATAACCCG
GAAAATATGCAGCCGGTAACATTATCCCTGCATGAAAAAATCAATGTACTGACCGCCGGGATGGCTATCGATCTTGAGAG
CCCGCTTTCTGACGATGACGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBH8NM45

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0H3F4N7

References