Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 106668..107325 | Replicon | plasmid unnamed1 |
| Accession | NZ_CP032192 | ||
| Organism | Salmonella enterica subsp. enterica serovar Senftenberg strain AR_0127 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | AM374_RS00665 | Protein ID | WP_000270043.1 |
| Coordinates | 106975..107325 (-) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | AM374_RS00660 | Protein ID | WP_000124640.1 |
| Coordinates | 106668..106970 (-) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AM374_RS00610 | 102302..102730 | + | 429 | WP_000591076.1 | hypothetical protein | - |
| AM374_RS00615 | 102788..103147 | + | 360 | WP_000422769.1 | hypothetical protein | - |
| AM374_RS00620 | 103147..103593 | + | 447 | WP_000919343.1 | hypothetical protein | - |
| AM374_RS00625 | 103590..104108 | + | 519 | WP_000210757.1 | nitrite reductase | - |
| AM374_RS00630 | 104108..104338 | + | 231 | WP_000972665.1 | hypothetical protein | - |
| AM374_RS00635 | 104325..105182 | + | 858 | WP_001167036.1 | hypothetical protein | - |
| AM374_RS27160 | 105094..105399 | + | 306 | WP_171820680.1 | hypothetical protein | - |
| AM374_RS00645 | 105402..105929 | + | 528 | WP_004201083.1 | thermonuclease family protein | - |
| AM374_RS00650 | 105987..106259 | + | 273 | WP_001043046.1 | HU family DNA-binding protein | - |
| AM374_RS00655 | 106348..106641 | + | 294 | WP_001239998.1 | hypothetical protein | - |
| AM374_RS00660 | 106668..106970 | - | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| AM374_RS00665 | 106975..107325 | - | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| AM374_RS00670 | 107488..108036 | + | 549 | WP_001061573.1 | hypothetical protein | - |
| AM374_RS00675 | 108290..109503 | + | 1214 | WP_139371347.1 | IS3 family transposase | - |
| AM374_RS00685 | 109690..109884 | + | 195 | WP_000343597.1 | hypothetical protein | - |
| AM374_RS00690 | 109895..110266 | + | 372 | WP_000516918.1 | hypothetical protein | - |
| AM374_RS00695 | 110259..110729 | + | 471 | WP_001281821.1 | hypothetical protein | - |
| AM374_RS00700 | 110744..111079 | - | 336 | WP_000683477.1 | hypothetical protein | - |
| AM374_RS00705 | 111176..111664 | + | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| AM374_RS00710 | 111667..112164 | + | 498 | WP_000062185.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..159356 | 159356 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 17237.68 Da Isoelectric Point: 5.5500
>T111293 WP_000270043.1 NZ_CP032192:c107325-106975 [Salmonella enterica subsp. enterica serovar Senftenberg]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
Download Length: 351 bp
>T111293 NZ_CP032192:c107325-106975 [Salmonella enterica subsp. enterica serovar Senftenberg]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 14882.85 Da Isoelectric Point: 5.5500
>AT111293 WP_000124640.1 NZ_CP032192:c106970-106668 [Salmonella enterica subsp. enterica serovar Senftenberg]
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Download Length: 303 bp
>AT111293 NZ_CP032192:c106970-106668 [Salmonella enterica subsp. enterica serovar Senftenberg]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|