110945

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2464591..2464775 Replicon chromosome
Accession NZ_CP032051
Organism Staphylococcus aureus strain O17

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SaO17_RS12760 Protein ID WP_000482647.1
Coordinates 2464668..2464775 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2464591..2464651 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO17_RS12735 2460046..2460213 - 168 WP_041204334.1 hypothetical protein -
SaO17_RS12745 2460444..2462177 - 1734 WP_000486497.1 ABC transporter ATP-binding protein/permease -
SaO17_RS12750 2462202..2463965 - 1764 WP_001064817.1 ABC transporter ATP-binding protein/permease -
- 2464591..2464651 + 61 - - Antitoxin
SaO17_RS12760 2464668..2464775 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SaO17_RS12765 2464909..2465295 - 387 WP_000779350.1 flippase GtxA -
SaO17_RS12770 2465563..2466705 + 1143 WP_118848162.1 glycerate kinase -
SaO17_RS12775 2466765..2467424 + 660 WP_000831299.1 hypothetical protein -
SaO17_RS12780 2467609..2468820 + 1212 WP_001191928.1 multidrug effflux MFS transporter -
SaO17_RS12785 2468943..2469416 - 474 WP_000456493.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T110945 WP_000482647.1 NZ_CP032051:c2464775-2464668 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T110945 NZ_CP032051:c2464775-2464668 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT110945 NZ_CP032051:2464591-2464651 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References