Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2174333..2174596 Replicon chromosome
Accession NZ_CP032051
Organism Staphylococcus aureus strain O17

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SaO17_RS11220 Protein ID WP_001802298.1
Coordinates 2174492..2174596 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2174333..2174497 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SaO17_RS11200 2170565..2171230 - 666 WP_001024100.1 SDR family oxidoreductase -
SaO17_RS11205 2171382..2171702 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SaO17_RS11210 2171704..2172684 + 981 WP_000019740.1 CDF family zinc efflux transporter CzrB -
SaO17_RS11215 2172950..2174041 + 1092 WP_000495692.1 hypothetical protein -
- 2174333..2174497 + 165 - - Antitoxin
SaO17_RS11220 2174492..2174596 - 105 WP_001802298.1 hypothetical protein Toxin
SaO17_RS14305 2174757..2175240 - 484 Protein_2085 recombinase family protein -
SaO17_RS11230 2175283..2176403 - 1121 Protein_2086 SAP domain-containing protein -
SaO17_RS11235 2177452..2178309 - 858 WP_000370943.1 Cof-type HAD-IIB family hydrolase -
SaO17_RS11240 2178377..2179159 - 783 WP_118848146.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T110942 WP_001802298.1 NZ_CP032051:c2174596-2174492 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T110942 NZ_CP032051:c2174596-2174492 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT110942 NZ_CP032051:2174333-2174497 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References