Detailed information of TA system TA110937

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1824658..1824838
• Replicon: chromosome
• Accession: NZ_CP032051
• Organism: Staphylococcus aureus strain O17

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SaO17_RS09085
• Protein ID: WP_001801861.1
• Coordinates: 1824658..1824753 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1824781..1824838 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SaO17_RS09050	1820062..1820688	+	627	WP_000669034.1	hypothetical protein	-
SaO17_RS09055	1820729..1821070	+	342	WP_000627544.1	DUF3969 family protein	-
SaO17_RS09060	1821171..1821743	+	573	WP_000414210.1	hypothetical protein	-
SaO17_RS09065	1822119..1822955	+	837	WP_000190484.1	ABC transporter ATP-binding protein	-
SaO17_RS09075	1823761..1824207	-	447	WP_000747806.1	DUF1433 domain-containing protein	-
SaO17_RS09085	1824658..1824753	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1824781..1824838	-	58	-	-	Antitoxin
SaO17_RS09090	1824876..1824977	+	102	WP_001791232.1	hypothetical protein	-
SaO17_RS09095	1824963..1825142	-	180	Protein_1719	transposase	-
SaO17_RS09100	1825330..1825704	-	375	WP_000695817.1	DUF1433 domain-containing protein	-
SaO17_RS09105	1825694..1826074	-	381	WP_001035978.1	DUF1433 domain-containing protein	-
SaO17_RS09110	1826282..1826722	-	441	WP_000759945.1	DUF1433 domain-containing protein	-
SaO17_RS09115	1826767..1828380	+	1614	WP_000926709.1	hypothetical protein	-
SaO17_RS09120	1828395..1828694	+	300	WP_000095391.1	WXG100 family type VII secretion target	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-122)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T110937 WP_001801861.1 NZ_CP032051:1824658-1824753 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T110937 NZ_CP032051:1824658-1824753 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT110937 NZ_CP032051:c1824838-1824781 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin