110520

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2260410..2260673 Replicon chromosome
Accession NZ_CP031890
Organism Staphylococcus aureus strain CFSAN082781

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag D1E87_RS11655 Protein ID WP_001802298.1
Coordinates 2260569..2260673 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2260410..2260574 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1E87_RS11635 2256593..2257258 - 666 WP_001024094.1 SDR family oxidoreductase -
D1E87_RS11640 2257410..2257730 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
D1E87_RS11645 2257732..2258712 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
D1E87_RS11650 2258978..2260069 + 1092 WP_000495671.1 lytic regulatory protein -
- 2260410..2260574 + 165 - - Antitoxin
D1E87_RS11655 2260569..2260673 - 105 WP_001802298.1 hypothetical protein Toxin
D1E87_RS11660 2260834..2261317 - 484 Protein_2201 recombinase family protein -
D1E87_RS11665 2261360..2262496 - 1137 WP_000115564.1 SAP domain-containing protein -
D1E87_RS11670 2262785..2262877 + 93 WP_001790138.1 hypothetical protein -
D1E87_RS11675 2263582..2264439 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
D1E87_RS11680 2264507..2265289 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T110520 WP_001802298.1 NZ_CP031890:c2260673-2260569 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T110520 NZ_CP031890:c2260673-2260569 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT110520 NZ_CP031890:2260410-2260574 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References