Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1925006..1925188 Replicon chromosome
Accession NZ_CP031890
Organism Staphylococcus aureus strain CFSAN082781

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag D1E87_RS09605 Protein ID WP_001801861.1
Coordinates 1925006..1925101 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1925129..1925188 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1E87_RS09555 1920666..1921292 + 627 Protein_1840 hypothetical protein -
D1E87_RS09560 1921333..1921677 + 345 WP_000627551.1 DUF3969 family protein -
D1E87_RS09565 1921775..1922326 + 552 WP_000414205.1 hypothetical protein -
D1E87_RS09570 1922544..1923185 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
D1E87_RS09575 1923299..1923484 - 186 WP_000809857.1 hypothetical protein -
D1E87_RS09580 1923486..1923662 - 177 WP_000375476.1 hypothetical protein -
D1E87_RS09585 1923673..1924056 - 384 WP_149557713.1 hypothetical protein -
D1E87_RS09595 1924660..1924803 - 144 WP_001549059.1 transposase -
D1E87_RS09605 1925006..1925101 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1925129..1925188 - 60 - - Antitoxin
D1E87_RS09610 1925224..1925325 + 102 WP_001791893.1 hypothetical protein -
D1E87_RS09615 1925303..1925479 - 177 Protein_1850 transposase -
D1E87_RS09620 1925673..1926050 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T110511 WP_001801861.1 NZ_CP031890:1925006-1925101 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T110511 NZ_CP031890:1925006-1925101 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT110511 NZ_CP031890:c1925188-1925129 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References