Detailed information of TA system TA110300

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 871999..872179
• Replicon: chromosome
• Accession: NZ_CP031839
• Organism: Staphylococcus aureus strain NX-T55

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: D1O27_RS04785
• Protein ID: WP_001801861.1
• Coordinates: 872084..872179 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	871999..872056 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D1O27_RS04765	867574..868254	+	681	Protein_848	DNA adenine methylase	-
D1O27_RS04770	868306..869478	-	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
D1O27_RS04780	869738..871433	+	1696	Protein_850	hypothetical protein	-
D1O27_RS04785	872084..872179	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
D1O27_RS04795	872631..873077	+	447	WP_000747805.1	DUF1433 domain-containing protein	-
D1O27_RS04800	873261..873817	+	557	Protein_853	ImmA/IrrE family metallo-endopeptidase	-
D1O27_RS04805	873949..874701	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
D1O27_RS04810	874728..875471	-	744	WP_175393121.1	exotoxin	-
D1O27_RS04815	875498..876124	-	627	WP_000669028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	849383..877888	28505
	-	flank	IS/Tn	-	-	868306..869478	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T110300 WP_001801861.1 NZ_CP031839:c872179-872084 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T110300 NZ_CP031839:c872179-872084 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT110300 NZ_CP031839:871999-872056 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin