Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 871999..872179 Replicon chromosome
Accession NZ_CP031839
Organism Staphylococcus aureus strain NX-T55

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag D1O27_RS04785 Protein ID WP_001801861.1
Coordinates 872084..872179 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 871999..872056 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1O27_RS04765 867574..868254 + 681 Protein_848 DNA adenine methylase -
D1O27_RS04770 868306..869478 - 1173 WP_000195429.1 IS256-like element IS256 family transposase -
D1O27_RS04780 869738..871433 + 1696 Protein_850 hypothetical protein -
- 871999..872056 + 58 - - Antitoxin
D1O27_RS04785 872084..872179 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
D1O27_RS04795 872631..873077 + 447 WP_000747805.1 DUF1433 domain-containing protein -
D1O27_RS04800 873261..873817 + 557 Protein_853 ImmA/IrrE family metallo-endopeptidase -
D1O27_RS04805 873949..874701 - 753 WP_000764922.1 staphylococcal enterotoxin type 27 -
D1O27_RS04810 874728..875471 - 744 WP_175393121.1 exotoxin -
D1O27_RS04815 875498..876124 - 627 WP_000669028.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 849383..877888 28505
- flank IS/Tn - - 868306..869478 1172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T110300 WP_001801861.1 NZ_CP031839:c872179-872084 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T110300 NZ_CP031839:c872179-872084 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT110300 NZ_CP031839:871999-872056 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References