Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 578542..578804 Replicon chromosome
Accession NZ_CP031839
Organism Staphylococcus aureus strain NX-T55

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag D1O27_RS03055 Protein ID WP_001802298.1
Coordinates 578542..578646 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 578641..578804 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1O27_RS03030 575339..576121 + 783 WP_031590911.1 ABC transporter ATP-binding protein -
D1O27_RS03035 576189..577046 + 858 WP_000370930.1 Cof-type HAD-IIB family hydrolase -
D1O27_RS03045 577704..577862 - 159 WP_001792784.1 hypothetical protein -
D1O27_RS14860 577855..578025 - 171 WP_001792292.1 transposase -
D1O27_RS03055 578542..578646 + 105 WP_001802298.1 hypothetical protein Toxin
- 578641..578804 - 164 - - Antitoxin
D1O27_RS03060 579088..580179 - 1092 WP_000495681.1 hypothetical protein -
D1O27_RS03065 580386..581558 + 1173 WP_000195429.1 IS256-like element IS256 family transposase -
D1O27_RS03070 581777..582757 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
D1O27_RS03075 582759..583079 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 580386..581558 1172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T110293 WP_001802298.1 NZ_CP031839:578542-578646 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T110293 NZ_CP031839:578542-578646 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT110293 NZ_CP031839:c578804-578641 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References