Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 296361..296545 Replicon chromosome
Accession NZ_CP031839
Organism Staphylococcus aureus strain NX-T55

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag D1O27_RS01525 Protein ID WP_000482647.1
Coordinates 296361..296468 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 296485..296545 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1O27_RS01500 291733..292206 + 474 WP_000456489.1 GyrI-like domain-containing protein -
D1O27_RS01505 292329..293540 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
D1O27_RS01510 293722..294381 - 660 WP_000831298.1 membrane protein -
D1O27_RS01515 294441..295583 - 1143 WP_001176863.1 glycerate kinase -
D1O27_RS01520 295841..296227 + 387 WP_000779360.1 flippase GtxA -
D1O27_RS01525 296361..296468 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 296485..296545 - 61 - - Antitoxin
D1O27_RS01535 297096..298859 + 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
D1O27_RS01540 298884..300617 + 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
D1O27_RS01550 300848..301015 + 168 WP_117346041.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T110290 WP_000482647.1 NZ_CP031839:296361-296468 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T110290 NZ_CP031839:296361-296468 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT110290 NZ_CP031839:c296545-296485 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References