Detailed information of TA system TA110283

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 938336..938516
• Replicon: chromosome
• Accession: NZ_CP031838
• Organism: Staphylococcus aureus strain QD-CD9

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: D1G35_RS05065
• Protein ID: WP_001801861.1
• Coordinates: 938421..938516 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	938336..938393 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D1G35_RS05045	933911..934591	+	681	Protein_902	DNA adenine methylase	-
D1G35_RS05050	934643..935815	-	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
D1G35_RS05060	936075..937770	+	1696	Protein_904	hypothetical protein	-
-	938336..938393	+	58	-	-	Antitoxin
D1G35_RS05065	938421..938516	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
D1G35_RS05075	938968..939414	+	447	WP_000747805.1	DUF1433 domain-containing protein	-
D1G35_RS05080	939598..940154	+	557	Protein_907	ImmA/IrrE family metallo-endopeptidase	-
D1G35_RS05085	940286..941038	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
D1G35_RS05090	941065..941808	-	744	WP_175393121.1	exotoxin	-
D1G35_RS05095	941835..942461	-	627	WP_000669028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	914388..945020	30632
	-	flank	IS/Tn	-	-	934643..935815	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T110283 WP_001801861.1 NZ_CP031838:c938516-938421 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T110283 NZ_CP031838:c938516-938421 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT110283 NZ_CP031838:938336-938393 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin