110276

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 646212..646474 Replicon chromosome
Accession NZ_CP031838
Organism Staphylococcus aureus strain QD-CD9

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag D1G35_RS03355 Protein ID WP_001802298.1
Coordinates 646212..646316 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 646311..646474 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1G35_RS03330 643009..643791 + 783 WP_031590911.1 ABC transporter ATP-binding protein -
D1G35_RS03335 643859..644716 + 858 WP_000370930.1 Cof-type HAD-IIB family hydrolase -
D1G35_RS03345 645374..645532 - 159 WP_001792784.1 hypothetical protein -
D1G35_RS14915 645525..645695 - 171 WP_001792292.1 transposase -
D1G35_RS03355 646212..646316 + 105 WP_001802298.1 hypothetical protein Toxin
- 646311..646474 - 164 - - Antitoxin
D1G35_RS03360 646758..647849 - 1092 WP_117346099.1 transcriptional regulator -
D1G35_RS03365 648115..649095 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
D1G35_RS03370 649097..649417 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
D1G35_RS03375 649569..650234 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T110276 WP_001802298.1 NZ_CP031838:646212-646316 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T110276 NZ_CP031838:646212-646316 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT110276 NZ_CP031838:c646474-646311 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References