Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 164036..164574 Replicon chromosome
Accession NZ_CP031746
Organism Auritidibacter sp. NML130574

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag DCC27_RS12275 Protein ID WP_199445857.1
Coordinates 164036..164263 (+) Length 76 a.a.

Antitoxin (Protein)


Gene name HigA2 Uniprot ID -
Locus tag DCC27_RS00860 Protein ID WP_110100392.1
Coordinates 164269..164574 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCC27_RS00825 160099..161184 + 1086 WP_110100193.1 redox-regulated ATPase YchF -
DCC27_RS00830 161332..161565 + 234 WP_110100006.1 Arc family DNA-binding protein -
DCC27_RS00835 161562..161987 + 426 WP_110100194.1 type II toxin-antitoxin system VapC family toxin -
DCC27_RS00840 162000..162536 + 537 WP_158524689.1 GNAT family N-acetyltransferase -
DCC27_RS00845 162682..162876 - 195 WP_146206388.1 hypothetical protein -
DCC27_RS00850 163080..163805 + 726 WP_110100197.1 hypothetical protein -
DCC27_RS12275 164036..164263 + 228 WP_199445857.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DCC27_RS00860 164269..164574 + 306 WP_110100392.1 helix-turn-helix domain-containing protein Antitoxin
DCC27_RS00865 164725..164958 + 234 WP_110100198.1 hypothetical protein -
DCC27_RS00870 164943..165317 + 375 WP_146206389.1 hypothetical protein -
DCC27_RS00875 165583..166347 + 765 WP_110100200.1 sulfite exporter TauE/SafE family protein -
DCC27_RS00885 167423..168145 + 723 WP_110100393.1 sulfite exporter TauE/SafE family protein -
DCC27_RS12065 168184..168660 + 477 WP_148707488.1 hypothetical protein -
DCC27_RS00895 168902..169288 + 387 WP_110100203.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(11-65)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-88)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8777.09 Da        Isoelectric Point: 9.8609

>T109990 WP_199445857.1 NZ_CP031746:164036-164263 [Auritidibacter sp. NML130574]
IVDSVAGSRHKNMKELRPGSSGRSELRVLFAFDPERVAIMLIAEDKIGDWKRWYKKHISLADDLFDEHLARLRRE

Download         Length: 228 bp

>T109990 NZ_CP031746:164036-164263 [Auritidibacter sp. NML130574]
ATCGTCGACAGTGTAGCCGGGTCCCGGCATAAGAATATGAAAGAGCTCAGGCCCGGCTCGTCTGGCCGGTCCGAGTTGCG
CGTTCTGTTCGCGTTCGATCCAGAGCGAGTGGCGATCATGCTGATCGCCGAAGATAAGATCGGCGATTGGAAACGCTGGT
ATAAGAAGCACATTTCGTTGGCCGACGACCTCTTCGACGAGCATCTGGCCCGACTGAGAAGAGAGTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11378.08 Da        Isoelectric Point: 9.9101

>AT109990 WP_110100392.1 NZ_CP031746:164269-164574 [Auritidibacter sp. NML130574]
MPKNLKDFVAEHPVDRGRVEAHKKRMLAEVRAYRLRELREQAGLTQAQLAERIGVGQRQVSKIEQGDLDSAKVGTIRSYL
EAVGGELSLEYVMGDQRMKVA

Download         Length: 306 bp

>AT109990 NZ_CP031746:164269-164574 [Auritidibacter sp. NML130574]
ATGCCAAAGAACCTGAAGGATTTCGTCGCCGAGCATCCTGTTGACCGGGGACGGGTTGAGGCGCACAAGAAGCGGATGCT
TGCTGAGGTTCGCGCCTACCGTCTGCGAGAGCTACGGGAGCAGGCCGGACTGACGCAAGCGCAGCTGGCAGAGCGCATTG
GCGTCGGGCAGCGGCAGGTTTCGAAGATCGAGCAAGGCGACCTCGACAGCGCGAAGGTTGGCACCATCCGCAGTTACCTT
GAGGCCGTCGGTGGCGAACTCTCCCTTGAGTACGTGATGGGAGACCAGCGAATGAAGGTCGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References