Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1722842..1723697 Replicon chromosome
Accession NZ_CP031695
Organism Erwinia billingiae strain TH88

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag D0N50_RS07755 Protein ID WP_151037023.1
Coordinates 1723209..1723697 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag D0N50_RS07750 Protein ID WP_151037022.1
Coordinates 1722842..1723183 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0N50_RS07735 1719366..1720313 - 948 WP_013202877.1 ABC transporter permease -
D0N50_RS07740 1720334..1721920 - 1587 WP_151037020.1 ABC transporter substrate-binding protein -
D0N50_RS07745 1722042..1722689 + 648 WP_151037021.1 DUF1028 domain-containing protein -
D0N50_RS07750 1722842..1723183 + 342 WP_151037022.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
D0N50_RS07755 1723209..1723697 + 489 WP_151037023.1 type II toxin-antitoxin system YhaV family toxin Toxin
D0N50_RS07760 1723869..1724609 + 741 WP_151037024.1 SDR family oxidoreductase -
D0N50_RS07765 1724721..1725623 - 903 WP_151038679.1 LysR family transcriptional regulator -
D0N50_RS07770 1725713..1726729 + 1017 WP_151037025.1 NADP-dependent oxidoreductase -
D0N50_RS07775 1726800..1727285 - 486 WP_151037026.1 GNAT family N-acetyltransferase -
D0N50_RS07780 1727482..1728579 - 1098 WP_013202868.1 NADH:flavin oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(13-112)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 19317.27 Da        Isoelectric Point: 10.0193

>T109874 WP_151037023.1 NZ_CP031695:1723209-1723697 [Erwinia billingiae]
MEYLEINGWKFYFHSCFLTQLAELQNKVLAMKQKDPQGFHKKKETKLLAAIEQIITRVIPANPLDTHFRQGNTLGQEYRH
WYRVKFLQQFRLFFRYSVPHRTIIIGWVNDFGTLRAYGSKTDAYRVFERMLKSGEPPDDWDVLLKHCQSDARVINSDISR
KF

Download         Length: 489 bp

>T109874 NZ_CP031695:1723209-1723697 [Erwinia billingiae]
ATGGAGTATTTGGAGATTAATGGATGGAAATTCTATTTTCATTCCTGTTTTCTGACGCAGCTGGCTGAACTTCAAAATAA
AGTCCTGGCGATGAAACAAAAGGATCCTCAGGGCTTTCACAAAAAGAAAGAAACCAAGCTGCTGGCGGCGATTGAGCAAA
TCATTACTCGGGTGATCCCGGCCAACCCACTGGACACCCACTTTCGGCAGGGAAATACCTTAGGCCAGGAATACCGGCAC
TGGTACCGCGTTAAATTCCTGCAGCAGTTTCGGTTATTCTTCCGCTACAGCGTGCCCCACAGAACCATCATTATTGGCTG
GGTAAATGACTTTGGCACGCTTCGCGCTTATGGTTCGAAAACAGATGCCTATAGGGTATTTGAACGGATGCTGAAGTCTG
GCGAACCCCCTGATGATTGGGATGTGCTGCTGAAGCATTGCCAATCAGACGCCAGGGTTATAAACAGCGATATTTCTCGG
AAATTTTGA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12668.30 Da        Isoelectric Point: 4.1675

>AT109874 WP_151037022.1 NZ_CP031695:1722842-1723183 [Erwinia billingiae]
MNVNMADVSLRAESRLTERSQTTIPAAIRDALQLKPGEFIEYALLPGGKVVMSRREEEEPEDPVVPQFLAFLENDMMTNP
HHIHAVPAEFWARIQQLTAGVEVDLDGPLTDDE

Download         Length: 342 bp

>AT109874 NZ_CP031695:1722842-1723183 [Erwinia billingiae]
ATGAATGTAAACATGGCAGACGTGTCTCTGCGCGCGGAGTCCCGACTCACTGAGCGTAGCCAGACCACCATCCCCGCAGC
GATTCGTGATGCGCTGCAGCTGAAGCCGGGAGAATTCATTGAATACGCTCTGCTGCCCGGCGGTAAAGTCGTTATGTCAC
GGCGGGAAGAAGAAGAACCGGAAGATCCGGTGGTCCCGCAATTTCTGGCTTTCCTCGAAAACGACATGATGACCAACCCG
CATCATATCCATGCAGTGCCAGCAGAATTTTGGGCGAGGATCCAGCAACTGACTGCTGGCGTTGAGGTCGATTTAGACGG
GCCGCTGACTGACGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References