Detailed information of TA system TA109865

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrG-as-bsrE/-
• Location: 2762887..2763137
• Replicon: chromosome
• Accession: NZ_CP031694
• Organism: Bacillus velezensis strain SRCM101368

Toxin (Protein)

• Gene name: bsrG
• Uniprot ID: L8EAY0
• Locus tag: DXY21_RS14065
• Protein ID: WP_009967548.1
• Coordinates: 2763021..2763137 (-)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2762887..2763026 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DXY21_RS14045	2758642..2759076	+	435	WP_160249453.1	SMI1/KNR4 family protein	-
DXY21_RS14050	2759120..2759890	-	771	WP_077723157.1	hypothetical protein	-
DXY21_RS14055	2760399..2762153	+	1755	WP_160249296.1	hypothetical protein	-
DXY21_RS14060	2762153..2762713	+	561	WP_014472060.1	SMI1/KNR4 family protein	-
-	2762887..2763026	+	140	NuclAT_0	-	Antitoxin
-	2762887..2763026	+	140	NuclAT_0	-	Antitoxin
-	2762887..2763026	+	140	NuclAT_0	-	Antitoxin
-	2762887..2763026	+	140	NuclAT_0	-	Antitoxin
DXY21_RS14065	2763021..2763137	-	117	WP_009967548.1	type I toxin-antitoxin system toxin BsrG	Toxin
DXY21_RS14070	2763387..2763590	+	204	WP_057080536.1	hypothetical protein	-
DXY21_RS14075	2763718..2764476	+	759	WP_160249297.1	sporulation protein YunB	-
DXY21_RS14080	2764693..2765025	+	333	WP_038458779.1	YolD-like family protein	-
DXY21_RS14085	2765018..2766268	+	1251	WP_160249298.1	UV damage repair protein UvrX	-
DXY21_RS14090	2766433..2767593	-	1161	WP_076983515.1	tetratricopeptide repeat protein	-
DXY21_RS14095	2767745..2768005	-	261	WP_014472510.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2722007..2889255	167248

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-38)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4336.39 Da
• Isoelectric Point: 10.1022

>T109865 WP_009967548.1 NZ_CP031694:c2763137-2763021 [Bacillus velezensis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Nucleotide

• Length: 117 bp

>T109865 NZ_CP031694:c2763137-2763021 [Bacillus velezensis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin

Nucleotide

• Length: 140 bp

>AT109865 NZ_CP031694:2762887-2763026 [Bacillus velezensis]
AAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCACCCCGGCTCTGTACGAAAAGCTGCCCATCAAAGGGCTTGCTCG
ATGTTGAATCTGCGTAGACCTAACCCTTTAAGGTTCCTAAGCTCAAGGGAAGGTCTATTT

Structures

Toxin

• AlphaFold DB: A0A7Z7EVU9

Antitoxin