Detailed information of TA system TA109751

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1100788..1100970
• Replicon: chromosome
• Accession: NZ_CP031673
• Organism: Staphylococcus aureus strain MOZ66

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: DD548_RS06085
• Protein ID: WP_001801861.1
• Coordinates: 1100875..1100970 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1100788..1100847 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DD548_RS06070	1099926..1100303	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
DD548_RS06075	1100497..1100673	+	177	Protein_1100	transposase	-
DD548_RS06080	1100651..1100752	-	102	WP_001791893.1	hypothetical protein	-
-	1100788..1100847	+	60	-	-	Antitoxin
DD548_RS06085	1100875..1100970	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
DD548_RS06095	1101173..1101316	+	144	WP_001549059.1	transposase	-
DD548_RS06105	1101920..1102303	+	384	WP_000070812.1	hypothetical protein	-
DD548_RS06110	1102314..1102490	+	177	WP_000375476.1	hypothetical protein	-
DD548_RS06115	1102492..1102677	+	186	WP_000809857.1	hypothetical protein	-
DD548_RS06120	1102791..1103432	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
DD548_RS06125	1103650..1104201	-	552	WP_000414205.1	hypothetical protein	-
DD548_RS06130	1104299..1104643	-	345	WP_000627551.1	DUF3969 family protein	-
DD548_RS06135	1104684..1105310	-	627	WP_000669046.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T109751 WP_001801861.1 NZ_CP031673:c1100970-1100875 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T109751 NZ_CP031673:c1100970-1100875 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT109751 NZ_CP031673:1100788-1100847 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin