Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 701831..702094 Replicon chromosome
Accession NZ_CP031673
Organism Staphylococcus aureus strain MOZ66

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DD548_RS03540 Protein ID WP_001802298.1
Coordinates 701831..701935 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 701930..702094 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DD548_RS03515 697215..697997 + 783 WP_117224530.1 ABC transporter ATP-binding protein -
DD548_RS03520 698065..698922 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
DD548_RS03525 699627..699719 - 93 WP_001790138.1 hypothetical protein -
DD548_RS03530 700008..701144 + 1137 WP_117224531.1 SAP domain-containing protein -
DD548_RS14925 701187..701670 + 484 Protein_661 recombinase family protein -
DD548_RS03540 701831..701935 + 105 WP_001802298.1 hypothetical protein Toxin
- 701930..702094 - 165 - - Antitoxin
DD548_RS03545 702419..704065 - 1647 WP_000277738.1 IS1182 family transposase -
DD548_RS03550 704411..705502 - 1092 WP_000495671.1 lytic regulatory protein -
DD548_RS03555 705768..706748 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
DD548_RS03560 706750..707070 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 702419..704065 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T109740 WP_001802298.1 NZ_CP031673:701831-701935 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T109740 NZ_CP031673:701831-701935 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT109740 NZ_CP031673:c702094-701930 [Staphylococcus aureus]
GTAGCAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References