Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | SprA2-SprA2AS/- |
Location | 2506171..2506355 | Replicon | chromosome |
Accession | NZ_CP031664 | ||
Organism | Staphylococcus aureus strain 28 |
Toxin (Protein)
Gene name | SprA2 | Uniprot ID | Q2FVI9 |
Locus tag | DD545_RS13200 | Protein ID | WP_000482650.1 |
Coordinates | 2506248..2506355 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | SprA2AS | ||
Locus tag | - | ||
Coordinates | 2506171..2506231 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DD545_RS13175 | 2501701..2501868 | - | 168 | WP_117207278.1 | hypothetical protein | - |
DD545_RS13185 | 2502099..2503832 | - | 1734 | Protein_2440 | ABC transporter ATP-binding protein | - |
DD545_RS13190 | 2503857..2505620 | - | 1764 | WP_001064838.1 | ABC transporter ATP-binding protein/permease | - |
- | 2506171..2506231 | + | 61 | - | - | Antitoxin |
DD545_RS13200 | 2506248..2506355 | - | 108 | WP_000482650.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
DD545_RS13205 | 2506489..2506875 | - | 387 | WP_000779358.1 | flippase GtxA | - |
DD545_RS13210 | 2507143..2508285 | + | 1143 | WP_001176863.1 | glycerate kinase | - |
DD545_RS13215 | 2508345..2509004 | + | 660 | WP_000831298.1 | membrane protein | - |
DD545_RS13220 | 2509186..2510397 | + | 1212 | WP_001192075.1 | multidrug effflux MFS transporter | - |
DD545_RS13225 | 2510520..2510993 | - | 474 | WP_000456489.1 | GyrI-like domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4011.78 Da Isoelectric Point: 11.0582
>T109697 WP_000482650.1 NZ_CP031664:c2506355-2506248 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK
Download Length: 108 bp
>T109697 NZ_CP031664:c2506355-2506248 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
Antitoxin
Download Length: 61 bp
>AT109697 NZ_CP031664:2506171-2506231 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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