Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2215632..2215895 Replicon chromosome
Accession NZ_CP031664
Organism Staphylococcus aureus strain 28

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DD545_RS11615 Protein ID WP_001802298.1
Coordinates 2215791..2215895 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2215632..2215796 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DD545_RS11595 2211815..2212480 - 666 WP_117207270.1 SDR family oxidoreductase -
DD545_RS11600 2212632..2212952 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DD545_RS11605 2212954..2213934 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
DD545_RS11610 2214200..2215291 + 1092 WP_000495671.1 lytic regulatory protein -
- 2215632..2215796 + 165 - - Antitoxin
DD545_RS11615 2215791..2215895 - 105 WP_001802298.1 hypothetical protein Toxin
DD545_RS14955 2216056..2216539 - 484 Protein_2148 recombinase family protein -
DD545_RS11625 2216582..2217718 - 1137 WP_000115564.1 SAP domain-containing protein -
DD545_RS11630 2218007..2218099 + 93 WP_001790138.1 hypothetical protein -
DD545_RS11635 2218803..2219660 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
DD545_RS11640 2219728..2220510 - 783 WP_117207271.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T109694 WP_001802298.1 NZ_CP031664:c2215895-2215791 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T109694 NZ_CP031664:c2215895-2215791 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT109694 NZ_CP031664:2215632-2215796 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References