109603

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 1543421..1544751 Replicon chromosome
Accession NZ_CP031649
Organism Pantoea agglomerans strain TH81

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag D0A61_RS07165 Protein ID WP_122458143.1
Coordinates 1543421..1544443 (-) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag D0A61_RS07170 Protein ID WP_031591302.1
Coordinates 1544440..1544751 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0A61_RS07160 1541118..1543295 + 2178 WP_122459596.1 catalase/peroxidase HPI -
D0A61_RS07165 1543421..1544443 - 1023 WP_122458143.1 HipA domain-containing protein Toxin
D0A61_RS07170 1544440..1544751 - 312 WP_031591302.1 HipA N-terminal domain-containing protein Antitoxin
D0A61_RS07175 1544736..1545080 - 345 WP_122458145.1 helix-turn-helix transcriptional regulator -
D0A61_RS07185 1545857..1546978 + 1122 WP_033758329.1 Gfo/Idh/MocA family oxidoreductase -
D0A61_RS07190 1547069..1547899 - 831 WP_122458147.1 glycosyltransferase family 8 protein -
D0A61_RS07195 1547912..1549294 - 1383 WP_061703798.1 FAD-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-302)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38542.13 Da        Isoelectric Point: 6.8346

>T109603 WP_122458143.1 NZ_CP031649:c1544443-1543421 [Pantoea agglomerans]
MNSERCLITLKRLKESELKTGYSTKGIRHLLGSLNVALSLPFTRSQFIQELPERQKGMSISGYQPKLSLRLEKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMPLRHDENRPDELAFVIKRYDRTASDNARLHQEQLDGAMG
LGDKYGRIDNHKAISYEKAAKFLNTRVNSSLKSKRDLFLRIVYAYVLGNNDFHLRNIGIILPPQGSPWLAPVYDFISVVP
YPAAFGEYLALPLLEREENNAGNAPGINSEYGEYLGADFILLAQGMDINPTLARKWLSEVVSHHQLIIDTYNESHMPESQ
REAVLDYVARRITLLAVTEI

Download         Length: 1023 bp

>T109603 NZ_CP031649:c1544443-1543421 [Pantoea agglomerans]
ATGAATTCAGAACGCTGCCTGATCACATTAAAACGGCTTAAAGAATCTGAGCTAAAAACCGGCTACTCAACAAAAGGCAT
CCGGCATCTGCTGGGTAGTCTGAATGTGGCTCTTAGCCTGCCGTTTACGCGCAGTCAGTTTATTCAGGAACTCCCTGAAC
GTCAGAAAGGCATGAGCATTTCAGGCTATCAACCCAAACTGTCGCTTCGCCTGGAAAAGGGAGAACTGGTGGTCGTCAGC
AATGATGGCACATATATCCTGAAACCCTCTCCGGAAGAATACCCACACCTGGCAGAAAACGAGCATGCCACTATGTGCGT
TATGCAGCGTCTGAAATTTGACGTACCCCCGTTCGGGCTGATGCCATTAAGACACGATGAAAATCGGCCAGACGAACTGG
CGTTTGTCATTAAAAGGTATGACCGGACAGCGTCAGATAACGCGAGATTACATCAGGAACAGCTGGATGGCGCGATGGGT
CTCGGCGATAAATATGGCAGGATTGATAATCATAAAGCCATCAGTTACGAGAAAGCCGCTAAATTCCTGAATACCAGAGT
GAACAGCAGTTTGAAGAGTAAACGTGACCTCTTTTTGCGCATCGTGTATGCCTATGTGCTGGGAAACAATGATTTTCATC
TGCGCAATATCGGGATTATCCTGCCTCCGCAGGGTTCACCCTGGCTGGCCCCGGTTTATGACTTTATCAGCGTTGTGCCC
TACCCTGCAGCGTTTGGAGAGTATTTAGCTTTGCCCCTGCTGGAACGCGAAGAAAATAATGCAGGAAACGCACCGGGGAT
CAATTCAGAGTACGGAGAATATCTGGGTGCAGACTTTATCCTGCTTGCCCAGGGTATGGATATTAATCCGACACTGGCAC
GAAAATGGCTTTCCGAGGTGGTGAGTCATCATCAGCTTATTATCGATACTTATAATGAAAGTCATATGCCTGAATCGCAG
CGGGAAGCCGTACTTGACTACGTGGCCCGAAGGATCACGTTACTGGCAGTGACCGAAATTTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11696.49 Da        Isoelectric Point: 4.7953

>AT109603 WP_031591302.1 NZ_CP031649:c1544751-1544440 [Pantoea agglomerans]
MARKIEVWLYNTLAGTLSEGQNGYTFCYLPTYVGCAISLSMPVRPEPYLSEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMENGNDLLGAVVFKEITS

Download         Length: 312 bp

>AT109603 NZ_CP031649:c1544751-1544440 [Pantoea agglomerans]
ATGGCTCGAAAAATAGAGGTGTGGCTTTACAACACGCTGGCAGGAACGCTGAGTGAAGGGCAAAACGGTTATACTTTCTG
CTACCTGCCCACTTATGTCGGCTGTGCGATATCTCTCAGCATGCCGGTAAGACCTGAGCCCTATTTAAGTGAAGAGCTAC
ATCCCTTCTTTAAAGGTTTAGCGCCGGAAGGCTGGTTGCGAAAACGCTATTCTGAAATTCAAAAAATTGATGATAAAGAT
CTGTTCGGCTTACTGATGGAAAATGGCAACGATTTGCTTGGGGCAGTCGTCTTTAAAGAGATAACATCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References