Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4346107..4346762 Replicon chromosome
Accession NZ_CP031648
Organism Pseudomonas fluorescens strain Pf275

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DZG01_RS20100 Protein ID WP_116833406.1
Coordinates 4346418..4346762 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DZG01_RS20095 Protein ID WP_003205391.1
Coordinates 4346107..4346421 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DZG01_RS20075 4342016..4342933 + 918 WP_116833405.1 LysR family transcriptional regulator -
DZG01_RS20080 4343177..4344190 + 1014 WP_109754830.1 GGDEF domain-containing protein -
DZG01_RS20085 4344283..4345026 + 744 WP_109754831.1 DUF72 domain-containing protein -
DZG01_RS20090 4345165..4345869 + 705 WP_109754832.1 hypothetical protein -
DZG01_RS20095 4346107..4346421 - 315 WP_003205391.1 helix-turn-helix domain-containing protein Antitoxin
DZG01_RS20100 4346418..4346762 - 345 WP_116833406.1 toxin Toxin
DZG01_RS20105 4346902..4347789 - 888 WP_109754834.1 heme o synthase -
DZG01_RS20110 4347801..4348136 - 336 WP_025211927.1 cytochrome o ubiquinol oxidase subunit IV -
DZG01_RS20115 4348137..4348763 - 627 WP_109754835.1 cytochrome o ubiquinol oxidase subunit III -
DZG01_RS20120 4348767..4350797 - 2031 WP_109754836.1 cytochrome o ubiquinol oxidase subunit I -
DZG01_RS20125 4350801..4351748 - 948 WP_003205397.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(47-87)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13666.64 Da        Isoelectric Point: 8.3922

>T109599 WP_116833406.1 NZ_CP031648:c4346762-4346418 [Pseudomonas fluorescens]
MRTLFFETTTFTATVGHYLTDDEYRLLQSYMLEHPEVGDVMPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLMNDRQFWM
FAIYDKDELVNLTSEQEKTLKRAIEAELNVRGTL

Download         Length: 345 bp

>T109599 NZ_CP031648:c4346762-4346418 [Pseudomonas fluorescens]
ATGCGTACCCTATTTTTTGAAACGACCACATTCACCGCCACGGTTGGCCATTACCTGACTGATGATGAGTATCGTCTGCT
TCAGTCCTATATGCTGGAGCATCCAGAGGTCGGTGACGTCATGCCACGTACCGGCGGCTTTCGTAAGCTGCGCTGGTTCG
ATGAGCGTCGTGGCAAAGGGAAGCGGGGTGGGTTGCGAGTCATTTACTATTGGCTCATGAACGATCGTCAGTTTTGGATG
TTCGCGATTTATGACAAGGACGAGTTGGTAAACCTGACCTCCGAGCAAGAGAAGACGCTCAAGCGCGCCATAGAAGCTGA
GTTGAACGTACGAGGTACCTTATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11771.76 Da        Isoelectric Point: 9.8409

>AT109599 WP_003205391.1 NZ_CP031648:c4346421-4346107 [Pseudomonas fluorescens]
MKKRDLFAEMMQGVEEMAAHREGKITLRQISIEDKPVPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp

>AT109599 NZ_CP031648:c4346421-4346107 [Pseudomonas fluorescens]
ATGAAAAAGCGCGATCTGTTTGCCGAGATGATGCAAGGCGTCGAGGAGATGGCCGCTCACCGCGAGGGCAAGATTACCCT
TCGCCAGATATCGATCGAAGACAAACCGGTTCCCGAGGTGTCGGCCCAGGAAATCGTGGCTTTGCGCGACAAGCTCCACA
TGTCCCAAGCCGTTTTCGCCAAGAGCATCAGGACCAGTCCAGGTACCCTGAGAAATTGGGAACAGGAAAAATCCAAGCCT
AACGCCCAGGCGGCTTTGTTGATCAAACTGGTCGAGAAGTTTCCAGATATGGTCGAACGACTTGGCGCTGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References