Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 2326864..2327379 Replicon chromosome
Accession NZ_CP031607
Organism Xanthomonas hortorum strain VT106

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DYQ48_RS09940 Protein ID WP_154844615.1
Coordinates 2326864..2327070 (+) Length 69 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DYQ48_RS09945 Protein ID WP_023903908.1
Coordinates 2327080..2327379 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DYQ48_RS09920 2322184..2323434 - 1251 WP_154844613.1 chemotaxis protein CheW -
DYQ48_RS09925 2323431..2324213 - 783 WP_154844614.1 ParA family protein -
DYQ48_RS09930 2324215..2325204 - 990 WP_006452731.1 flagellar motor protein MotD -
DYQ48_RS09935 2325212..2325952 - 741 WP_006452732.1 flagellar motor protein -
DYQ48_RS09940 2326864..2327070 + 207 WP_154844615.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DYQ48_RS09945 2327080..2327379 + 300 WP_023903908.1 HigA family addiction module antidote protein Antitoxin
DYQ48_RS09950 2327549..2329207 - 1659 WP_055826896.1 chemotaxis protein CheA -
DYQ48_RS09955 2329210..2329836 - 627 WP_006450905.1 protein phosphatase CheZ -
DYQ48_RS09960 2329836..2330228 - 393 WP_002813536.1 chemotaxis response regulator CheY -
DYQ48_RS09965 2330264..2331037 - 774 WP_023903918.1 RNA polymerase sigma factor FliA -
DYQ48_RS09970 2331034..2331918 - 885 WP_006451802.1 MinD/ParA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(3-68)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(4-88)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7784.81 Da        Isoelectric Point: 6.2041

>T109518 WP_154844615.1 NZ_CP031607:2326864-2327070 [Xanthomonas hortorum]
MQAVAERKLQLLDSAQTLEFLRSPPGNRLELLAGTRAGQHSIRINDQWRVCFVWTDAGPEHVEIVDYH

Download         Length: 207 bp

>T109518 NZ_CP031607:2326864-2327070 [Xanthomonas hortorum]
ATGCAAGCTGTAGCCGAACGGAAGCTGCAATTGCTGGATTCGGCGCAGACGCTGGAGTTCTTGCGCAGCCCGCCGGGCAA
TCGGCTTGAGCTTCTTGCGGGTACGCGTGCAGGTCAGCACAGCATCCGCATCAATGACCAATGGCGTGTGTGCTTTGTCT
GGACTGACGCCGGCCCCGAGCACGTTGAGATTGTCGATTACCACTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10903.58 Da        Isoelectric Point: 10.7753

>AT109518 WP_023903908.1 NZ_CP031607:2327080-2327379 [Xanthomonas hortorum]
MRLTNKLRAIHPGEILREDFMLPLGLTINGLARALDVPATRIHSIVHGERAISADTAARLARHFGGDAASWLALQATYEL
KTLPNRSEIERNVQPRVAA

Download         Length: 300 bp

>AT109518 NZ_CP031607:2327080-2327379 [Xanthomonas hortorum]
ATGCGACTCACCAACAAACTGCGCGCCATCCATCCTGGCGAAATCCTGCGGGAAGATTTCATGCTGCCGCTGGGGCTGAC
CATCAACGGCCTGGCGCGGGCGCTGGATGTACCGGCAACGCGCATCCACAGCATCGTGCATGGCGAGCGTGCCATCAGCG
CCGATACCGCAGCGCGGCTTGCACGCCACTTCGGTGGCGATGCGGCGTCCTGGCTCGCGCTGCAGGCCACGTATGAACTC
AAGACCTTGCCCAACCGCAGCGAGATCGAGCGCAACGTGCAGCCGCGTGTGGCGGCCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References