Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 926861..927140 Replicon chromosome
Accession NZ_CP031537
Organism Staphylococcus aureus strain WCH-SK2

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag LR49_RS05060 Protein ID WP_001802298.1
Coordinates 927036..927140 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 926861..927040 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LR49_RS05040 923183..923848 - 666 WP_001024094.1 SDR family oxidoreductase -
LR49_RS05045 924000..924320 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LR49_RS05050 924322..925302 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
LR49_RS05055 925568..926659 + 1092 WP_000495671.1 lytic regulatory protein -
- 926861..927040 + 180 - - Antitoxin
LR49_RS05060 927036..927140 - 105 WP_001802298.1 hypothetical protein Toxin
LR49_RS15280 927301..927784 - 484 Protein_913 recombinase family protein -
LR49_RS05070 927827..928963 - 1137 WP_000115564.1 SAP domain-containing protein -
LR49_RS05075 929252..929344 + 93 WP_001790138.1 hypothetical protein -
LR49_RS05080 930049..930906 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
LR49_RS05085 930974..931756 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T109332 WP_001802298.1 NZ_CP031537:c927140-927036 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T109332 NZ_CP031537:c927140-927036 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 180 bp

>AT109332 NZ_CP031537:926861-927040 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References